Paroxysmal cold hemoglobinuria: a difficult diagnosis in adult patients
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DOI: 10.1111/trf.13888
Abstract: Paroxysmal cold hemoglobinuria (PCH) is a rare form of autoimmune hemolytic anemia caused by a biphasic (Donath‐Landsteiner [DL]) immunoglobulin G autoantibody. Estimates of disease frequency after syphilis are lacking and the diagnostic yield of testing… read more here.
Keywords: diagnosis adult; difficult diagnosis; paroxysmal cold; hemoglobinuria difficult ... See more keywords
Paroxysmal Cold Hemoglobinuria Successfully Treated with Complement Inhibition
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DOI: 10.1182/blood-2019-126365
Abstract: Introduction: Paroxysmal cold hemoglobinuria (PCH) is a rare autoimmune hemolytic anemia (AIHA) that causes intravascular hemolysis and profound, sometimes life-threatening anemia. It most commonly occurs in children following viral infection, and presents with acute onset… read more here.
Keywords: cold hemoglobinuria; complement; paroxysmal cold; day ... See more keywords
Paroxysmal cold hemoglobinuria successfully treated with complement inhibition.
Sign Up to like & getrecommendations! Published in 2019 at "Blood advances"
DOI: 10.1182/bloodadvances.2019000897
Abstract: This is the first-ever demonstration of successful treatment of paroxysmal cold hemoglobinuria using the complement inhibitor eculizumab. read more here.
Keywords: cold hemoglobinuria; hemoglobinuria successfully; paroxysmal cold; successfully treated ... See more keywords