When Cold Is Hot: Immune Checkpoint Inhibition Therapy for Rhabdoid Tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer cell"
DOI: 10.1016/j.ccell.2019.11.006
Abstract: Carcinogen-induced cancers typically have high mutation burdens and an inflamed microenvironment and thus are poised to respond to immune checkpoint inhibitors (ICIs). However, cancers with loss-of-function mutations in the SWI/SNF complex have few additional mutations… read more here.
Keywords: immune checkpoint; cold hot; checkpoint inhibition; checkpoint ... See more keywords
Converting Cold into Hot Tumors by Combining Immunotherapies
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.08.031
Abstract: In a small phase Ib study in this issue of Cell, Ribas et al. report that the combination of intralesional injection of a modified human herpes simplex virus and systemic anti-PD-1 treatment resulted in a 62%… read more here.
Keywords: converting cold; cold hot; combining immunotherapies; tumors combining ... See more keywords
New insights into molecular mechanisms of "Cold or Hot" nature of food: When East meets West.
Sign Up to like & getrecommendations! Published in 2021 at "Food research international"
DOI: 10.1016/j.foodres.2021.110361
Abstract: Traditional Chinese medicines are largely adopted in China and have a key importance in the world medical system. Cold-hot nature is the important characteristics of food and Chinese Materia Medica in the traditional Chinese medicine,… read more here.
Keywords: nature food; medicine; cold hot; hot nature ... See more keywords
Analysis of Natural Organic Matter in Water from Cold and Hot Mineral Springs in South Korea Using 15T FT-ICR-MS
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01697
Abstract: The natural organic matter (NOM) properties in water from cold and hot mineral springs in South Korea are not well documented. We analyzed the characteristics of NOM in water from 25 cold and hot mineral… read more here.
Keywords: south korea; hot mineral; cold hot; water ... See more keywords
Solar and Geomagnetic Activity Impact on Occurrence and Spatial Size of Cold and Hot Polar Cap Patches
Sign Up to like & getrecommendations! Published in 2021 at "Geophysical Research Letters"
DOI: 10.1029/2021gl094526
Abstract: This paper is a statistical survey of polar cap patches in relation to solar and geomagnetic activity. Ten thousand six hundred eighty‐eight patches have been identified from in situ plasma observations of the Defense Meteorological… read more here.
Keywords: geomagnetic activity; solar geomagnetic; hot patches; cold hot ... See more keywords
Heat flowing from cold to hot without external intervention by using a “thermal inductor”
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aat9953
Abstract: We show that heat can flow from cold to hot using a thermal inductor, without violating the second law of thermodynamics. The cooling of boiling water all the way down to freezing, by thermally connecting… read more here.
Keywords: without external; using thermal; cold hot; heat ... See more keywords
N7-methylguanosine-related lncRNAs: Predicting the prognosis and diagnosis of colorectal cancer in the cold and hot tumors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.952836
Abstract: Background: 7-Methylguanosine(m7G) contributes greatly to its pathogenesis and progression in colorectal cancer. We proposed building a prognostic model of m7G-related LncRNAs. Our prognostic model was used to identify differences between hot and cold tumors. Methods:… read more here.
Keywords: m7g related; cold hot; related lncrnas; colorectal cancer ... See more keywords
Predicting Prognosis and Distinguishing Cold and Hot Tumors in Bladder Urothelial Carcinoma Based on Necroptosis-Associated lncRNAs
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.916800
Abstract: Background In reference to previous studies, necroptosis played an important role in cancer development. Our team decided to explore the potential prognostic values of long non-coding RNAs (lncRNAs) associated with necroptosis in bladder urothelial carcinoma… read more here.
Keywords: hot tumors; cold hot; bladder urothelial; associated lncrnas ... See more keywords
Necroptosis-associated long noncoding RNAs can predict prognosis and differentiate between cold and hot tumors in ovarian cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.967207
Abstract: Objective The mortality rate of ovarian cancer (OC) is the highest among all gynecologic cancers. To predict the prognosis and the efficacy of immunotherapy, we identified new biomarkers. Methods The Cancer Genome Atlas (TCGA) and… read more here.
Keywords: hot tumors; cold hot; ovarian cancer; necroptosis associated ... See more keywords
A Song of Ice and Fire: Cold and Hot Properties of Traditional Chinese Medicines
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.598744
Abstract: The theory of cold and hot properties is the basic theory of traditional Chinese medicines (TCMs) and has been successfully applied to combat human diseases for thousands of years. Although the theory of cold and… read more here.
Keywords: traditional chinese; theory; hot properties; cold hot ... See more keywords
A Comparative Study of the Antihypertensive and Cardioprotective Potentials of Hot and Cold Aqueous Extracts of Hibiscus sabdariffa L. in Relation to Their Metabolic Profiles
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.840478
Abstract: Ethnopharmacological relevance: Since ancient times, Hibiscus sabdariffa L. calyces have been used as a folk remedy for the treatment of hypertension. However, it is questionable as to whether there is a difference in the antihypertensive… read more here.
Keywords: study; hibiscus sabdariffa; cold aqueous; cold hot ... See more keywords