Protein–protein interaction network of E. coli K‐12 has significant high‐dimensional cavities: new insights from algebraic topological studies
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13437
Abstract: As a model system, Escherichia coli has been used to study various life processes. A dramatic paradigm shift has occurred in recent years, with the study of single proteins moving toward the study of dynamically interacting… read more here.
Keywords: network; dimensional cavities; ppi network; high dimensional ... See more keywords
Suppression of Sepsis Cytokine Storm by Escherichia Coli Cell Wall‐Derived Carbon Dots
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DOI: 10.1002/adma.202414237
Abstract: Sepsis is a life‐threatening disease caused by a dysregulated immune response to infection, often involving the translocation of Gram‐negative bacteria such as Escherichia coli (E. coli) into the bloodstream, triggering a cytokine storm. Despite its… read more here.
Keywords: carbon dots; coli; cytokine storm; derived carbon ... See more keywords
Artificial Diploid Escherichia coli by a CRISPR Chromosome‐Doubling Technique
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DOI: 10.1002/advs.202205855
Abstract: Synthetic biology has been represented by the creation of artificial life forms at the genomic scale. In this work, a CRISPR‐based chromosome‐doubling technique is designed to first construct an artificial diploid Escherichia coli cell. The… read more here.
Keywords: chromosome doubling; diploid; doubling technique; diploid escherichia ... See more keywords
Multidimensional Engineering of Escherichia coli for Efficient Adipic Acid Synthesis From Cyclohexane
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DOI: 10.1002/advs.202411938
Abstract: Adipic acid (AA), a key aliphatic dicarboxylic acid, is conventionally manufactured through energy‐intensive, multi‐step chemical processes with significant environmental impacts. In contrast, biological production methods offer more sustainable alternatives but are often limited by low… read more here.
Keywords: escherichia coli; adipic acid; coli efficient; coli ... See more keywords
Genome-scale Metabolic Modeling Guided Escherichia coli Engineering for De Novo Biosynthesis of Chrysanthemic Acid.
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DOI: 10.1002/advs.202512736
Abstract: Chrysanthemic acid is an unconventional monoterpene moiety of the natural pesticide pyrethrins with notable anti‐insect activity, making its industrial biosynthesis a promising avenue for sustainable agriculture. Here, an E. coli cell factory is designed and… read more here.
Keywords: genome scale; chrysanthemic acid; coli; biosynthesis ... See more keywords
Expanding the Spectrum: Modified Bacteriocin Nisin as a Trojan Horse Against Gram‐Negative Salmonella Typhimurium and Escherichia coli
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DOI: 10.1002/biot.70019
Abstract: Nisin is an antimicrobial peptide widely used as a biopreservative to extend shelf life and control foodborne pathogens, particularly Gram‐positive bacteria such as Listeria monocytogenes. However, its efficacy against Gram‐negative bacteria is limited due to… read more here.
Keywords: gram negative; spectrum; coli; typhimurium escherichia ... See more keywords
Metabolic engineering of isopropyl alcohol‐producing Escherichia coli strains with 13C‐metabolic flux analysis
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DOI: 10.1002/bit.26390
Abstract: Metabolic engineering of isopropyl alcohol (IPA)‐producing Escherichia coli strains was conducted along with 13C‐metabolic flux analysis (MFA). A metabolically engineered E. coli strain expressing the adc gene derived from Clostridium acetobutylicum and the IPADH gene… read more here.
Keywords: metabolic engineering; flux; isopropyl alcohol; coli ... See more keywords
Strain engineering for high‐level 5‐aminolevulinic acid production in Escherichia coli
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DOI: 10.1002/bit.27547
Abstract: Herein, we report the development of a microbial bioprocess for high‐level production of 5‐aminolevulinic acid (5‐ALA), a valuable non‐proteinogenic amino acid with multiple applications in medical, agricultural, and food industries, using Escherichia coli as a… read more here.
Keywords: engineering; high level; production; coli ... See more keywords
Chromosome evolution of Escherichia coli Nissle 1917 for high‐level production of heparosan
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DOI: 10.1002/bit.28315
Abstract: Heparosan is a crucial‐polysaccharide precursor for the chemoenzymatic synthesis of heparin, a widely used anticoagulant drug. Presently, heparosan is mainly extracted with the potential risk of contamination from Escherichia coli strain K5, a pathogenic bacterium… read more here.
Keywords: nissle 1917; chromosome evolution; escherichia coli; kps locus ... See more keywords
Metabolic Engineering and Adaptive Evolution of Escherichia coli for Enhanced Conversion of D‑Xylose to D‐Glucaric Acid Mediated by Methanol
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DOI: 10.1002/bit.28974
Abstract: d‐Glucaric acid is a value‐added dicarboxylic acid that can be utilized in the chemical, food, and pharmaceutical industries. Due to the complex process and environmental pollution associated with the chemical production of d‐glucaric acid, bioconversion… read more here.
Keywords: adaptive evolution; coli; metabolic engineering; glucaric acid ... See more keywords
Kinetic resolution of N-acetyl-DL-alanine methyl ester using immobilized Escherichia coli cells bearing recombinant esterase from Bacillus cereus.
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DOI: 10.1002/chir.22863
Abstract: D-alanine is widely used in medicine, food, additives, cosmetics, and other consumer items. Esterase derived from Bacillus cereus WZZ001 exhibits high hydrolytic activity and stereoselectivity. In this study, we expressed the esterase gene in Escherichia… read more here.
Keywords: acetyl alanine; alanine; resolution; alanine methyl ... See more keywords