Design and Synthesis of TASIN Analogues Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC).
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DOI: 10.1021/acs.jmedchem.9b00532
Abstract: Despite advances in targeted anticancer therapies, there are still no small-molecule-based therapies available that specifically target colorectal cancer (CRC) development and progression, the second leading cause of cancer deaths. We previously disclosed the discovery of… read more here.
Keywords: colorectal cancer; chemistry; polyposis coli; coli apc ... See more keywords