Improved production of 2'-fucosyllactose in engineered Escherichia coli by expressing putative α-1,2-fucosyltransferase, WcfB from Bacteroides fragilis.
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DOI: 10.1016/j.jbiotec.2016.11.033
Abstract: 2'-Fucosyllactose (2-FL) is one of most abundant oligosaccharides in human milk, which is involved in many biological functions for infant health. Since 2-FL has a great potential in application to functional food materials and pharmaceuticals,… read more here.
Keywords: fucosyltransferase; putative fucosyltransferase; production; bacteroides fragilis ... See more keywords
Tumor-Colonizing E. coli Expressing Both Collagenase and Hyaluronidase Enhances Therapeutic Efficacy of Gemcitabine in Pancreatic Cancer Models
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DOI: 10.3390/biom14111458
Abstract: Desmoplasia is a hallmark feature of pancreatic ductal adenocarcinoma (PDAC) that contributes significantly to treatment resistance. Approaches to enhance drug delivery into fibrotic PDAC tumors continue to be an important unmet need. In this study,… read more here.
Keywords: collagenase hyaluronidase; tumor colonizing; efficacy; coli expressing ... See more keywords
Production of cinnamates and benzoates glucose esters by bioconversion using Escherichia coli expressing a glucosyltransferase from sweet potato
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DOI: 10.5511/plantbiotechnology.24.0705a
Abstract: Sweet potatoes (Ipomoea batatas) produce glucose esters from cinnamates during stress responses. We isolated a glucosyltransferase, IbGT1 (UGT84A20), from sweet potato and characterized its recombinant enzyme heterologously expressed in Escherichia coli. The recombinant IbGT1 enzyme… read more here.
Keywords: escherichia coli; glucose esters; coli expressing; bioconversion using ... See more keywords