Genome-wide identification of probiotic Escherichia coli Nissle 1917 (EcN) fitness genes during adhesion to the intestinal epithelial cells Caco-2.
Sign Up to like & getrecommendations! Published in 2021 at "Gene"
DOI: 10.1016/j.gene.2021.145890
Abstract: Escherichia coli Nissle 1917 (EcN) is an efficient probiotic strain extensively used worldwide because of its several health benefits. Adhesion to the intestinal cells is one of the prerequisites for a probiotic strain. To identify… read more here.
Keywords: escherichia coli; 1917 ecn; adhesion; coli nissle ... See more keywords
E. coli Nissle 1917 modulates host glucose metabolism without directly acting on glucose
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DOI: 10.1038/s41598-021-02431-8
Abstract: Managing postprandial glycemic response, or the increase in blood sugar following a meal, is a crucial component to maintaining healthy blood sugar in patients with diabetes. To test whether oral probiotics can impact postprandial glycemic… read more here.
Keywords: glycemic response; glucose metabolism; coli nissle; glucose ... See more keywords
Effects of Supernatants from Escherichia coli Nissle 1917 and Faecalibacterium prausnitzii on Intestinal Epithelial Cells and a Rat Model of 5-Fluorouracil-Induced Mucositis
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DOI: 10.1080/01635581.2017.1263747
Abstract: ABSTRACT Faecalibacterium prausnitzii (Fp) and Escherichia coli Nissle 1917 (EcN) are probiotics, which have been reported to ameliorate certain gastrointestinal disorders. We evaluated the effects of supernatants (SN) derived from Fp and EcN on 5-fluorouracil… read more here.
Keywords: effects supernatants; mucositis; faecalibacterium prausnitzii; escherichia coli ... See more keywords
Prospective and challenges of live bacterial therapeutics from a superhero Escherichia coli Nissle 1917.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in microbiology"
DOI: 10.1080/1040841x.2022.2109405
Abstract: Escherichia coli Nissle 1917 (EcN), the active component of Mutaflor(R), is a notable probiotic from Gram-negative to treat Crohn's disease and irritable bowel syndrome. Therefore, a comprehensive genomic database maximizes the systemic probiotic assessment to… read more here.
Keywords: engineered ecn; nissle 1917; coli nissle; escherichia coli ... See more keywords
Engineered Escherichia coli Nissle 1917 with urate oxidase and an oxygen-recycling system for hyperuricemia treatment
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2070391
Abstract: ABSTRACT Hyperuricemia is the second most prevalent metabolic disease to human health after diabetes. Only a few clinical drugs are available, and most of them have serious side effects. The human body does not have… read more here.
Keywords: coli nissle; escherichia coli; engineered escherichia; urate oxidase ... See more keywords
Probiotic Escherichia coli Nissle 1917 inhibits bacterial persisters that survive fluoroquinolone treatment
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Microbiology"
DOI: 10.1111/jam.15541
Abstract: Bacterial persisters are rare phenotypic variants in clonal bacterial cultures that can endure antimicrobial therapy and potentially contribute to infection relapse. Here, we investigate the potential of leveraging microbial interactions to disrupt persisters as they… read more here.
Keywords: nissle 1917; coli nissle; probiotic escherichia; escherichia coli ... See more keywords
Effect of Probiotic E. coli Nissle 1917 Supplementation on the Growth Performance, Immune Responses, Intestinal Morphology, and Gut Microbes of Campylobacter jejuni Infected Chickens
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00337-22
Abstract: Campylobacter jejuni is the most common cause of bacterial foodborne gastroenteritis and holds significant public health importance. The continuing increase of antibiotic-resistant Campylobacter necessitates the development of antibiotic-alternative approaches to control infections in poultry and… read more here.
Keywords: nissle 1917; coli nissle; campylobacter jejuni; immune responses ... See more keywords
Probiotic Escherichia coli Nissle 1917-derived outer membrane vesicles enhance immunomodulation and antimicrobial activity in RAW264.7 macrophages
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DOI: 10.1186/s12866-020-01953-x
Abstract: Background Probiotic Escherichia coli Nissle 1917 (EcN) has been widely studied for the treatment of intestinal inflammatory diseases and infectious diarrhea, but the mechanisms by which they communicate with the host are not well-known. Outer… read more here.
Keywords: ecn omvs; microscopy; escherichia coli; coli nissle ... See more keywords
Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biological Engineering"
DOI: 10.1186/s13036-019-0189-9
Abstract: Traditional cancer therapies, such as surgery treatment, radiotherapy, and chemotherapy, often fail to completely eliminate tumor cells in an anaerobic microenvironment of tumor regions.In contrast to these traditional cancer therapies, the use of targeted delivery… read more here.
Keywords: tum; ecn; coli nissle; cancer ... See more keywords
Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008029
Abstract: Although Escherichia coli Nissle 1917 (EcN) has been used therapeutically for over a century, the determinants of its probiotic properties remain elusive. EcN produces two siderophore-microcins (Mcc) responsible for an antagonistic activity against other Enterobacteriaceae.… read more here.
Keywords: escherichia coli; coli nissle; ecn; antagonistic activity ... See more keywords
Treatment with Saccharomyces boulardii and Escherichia coli Nissle is safe and associated with reduced nosocomial transmission of vanB vancomycin-resistant Enterococcus faecium on an early rehabilitation ward in Germany: a retrospective analysis
Sign Up to like & getrecommendations! Published in 2019 at "Therapeutics and Clinical Risk Management"
DOI: 10.2147/tcrm.s179208
Abstract: Purpose According to the WHO vancomycin-resistant Enterococcus faecium (VRE) belongs to the microorganisms for which new antibiotics are urgently needed. Depending on the type of vancomycin resistance vanA gene VRE is differentiated from vanB VRE… read more here.
Keywords: coli nissle; number; vre; vancomycin ... See more keywords