RNA polymerase III initiation on coligo DNA templates containing loops of variable sequence, size and nucleotide chemistry.
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DOI: 10.1016/j.gene.2016.09.001
Abstract: Circularized oligonucleotides, or coligos, were previously found to serve as RNA polymerase III (Pol III) templates in vitro and in human tissue culture cells. Here we randomized the 12-nucleotide larger loop (L-loop) of a well… read more here.
Keywords: initiation; chemistry; coligo; pol iii ... See more keywords