Identification of a novel adjuvant loperamide that enhances the antibacterial activity of colistin against MCR-1-positive pathogens in vitro/vivo.
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DOI: 10.1093/lambio/ovad025
Abstract: Severe infection with MDR Enterobacterales caused by the plasmid-induced colistin resistance gene MCR-1 is a serious public health challenge. In this case, it is necessary and pressing to find a treatment to overcome antibiotic resistance.… read more here.
Keywords: loperamide; mcr positive; colistin; colistin mcr ... See more keywords