Intestinal carriage of colistin resistant Enterobacteriaceae in hospitalized patients from an Indian center.
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2020.114998
Abstract: There is limited data on the gut colonization rate of colistin resistant (Col-R) bacteria in patients and healthy volunteers in India. Aim of this study was to investigate the stool carriage rate of Col-R in… read more here.
Keywords: colistin; intestinal carriage; colistin resistant; enterobacteriaceae ... See more keywords
Synergistic activity of colistin with azidothymidine against colistin-resistant Klebsiella pneumoniae clinical isolates collected from inpatients in Greek hospitals.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2019.02.021
Abstract: BACKGROUND New antibiotics are urgently needed to treat multi-drug resistant infections; however, production of novel antibiotics is diminishing. Synergistic combination drug therapy to enhance the activity of available antibiotics may improve management of patients with… read more here.
Keywords: activity colistin; colistin; colistin resistant; klebsiella pneumoniae ... See more keywords
Draft genome sequence of mcr-1-mediated colistin-resistant Escherichia coli ST359 from chicken carcasses in Northeastern Brazil.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2020.08.016
Abstract: OBJECTIVES Considering that polymyxin is a drug of last resort in the treatment of humans infected by multidrug-resistant bacteria, the occurrence of plasmid-mediated colistin resistance mcr gene among Gram-negative bacteria in foods must be investigated.… read more here.
Keywords: coli; colistin resistant; mcr; mediated colistin ... See more keywords
Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds.
Sign Up to like & getrecommendations! Published in 2023 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.2c00417
Abstract: Colistin, typically viewed as the antibiotic of last resort to treat infections caused by multidrug-resistant (MDR) Gram-negative bacteria, had fallen out of favor due to toxicity issues. The recent increase in clinical usage of colistin… read more here.
Keywords: colistin resistant; colistin; multidrug resistant; negative bacteria ... See more keywords
Constraint-based modeling identifies new putative targets to fight colistin-resistant A. baumannii infections
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03416-2
Abstract: Acinetobacter baumannii is a clinical threat to human health, causing major infection outbreaks worldwide. As new drugs against Gram-negative bacteria do not seem to be forthcoming, and due to the microbial capability of acquiring multi-resistance,… read more here.
Keywords: baumannii infections; constraint based; based modeling; colistin resistant ... See more keywords
Restoring colistin sensitivity in colistin-resistant E. coli: Combinatorial use of MarR inhibitor with efflux pump inhibitor
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-56325-x
Abstract: Antibiotics like colistin are the last resort to deal with infections by carbapenem-resistant Enterobacteriaceae (CREB). Resistance to colistin severely restricts therapeutic options. To tackle this dire situation, urgent measures to restore colistin sensitivity are needed.… read more here.
Keywords: inhibitor; resistant coli; colistin; colistin resistant ... See more keywords
Mutations at Novel Sites in pmrA/B and lpxA/D Genes and Absence of Reduced Fitness in Colistin-Resistant Acinetobacter baumannii from a Tertiary Care Hospital, India.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial drug resistance"
DOI: 10.1089/mdr.2020.0023
Abstract: Background: Colistin resistance in Acinetobacter baumannii, the last resort drug for serious infections, is emerging worldwide. There has been paucity of data on this aspect from India, which is one of the largest producers of… read more here.
Keywords: pmra lpxa; colistin; lpxa genes; resistance ... See more keywords
Acquisition of Enterobacterales carrying the colistin resistance gene mcr following travel to the tropics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of travel medicine"
DOI: 10.1093/jtm/taac141
Abstract: BACKGROUND Colistin is an antibiotic of last resort in the management of highly drug-resistant Enterobacterales infections. Travel to some destinations presents a high risk of acquiring multidrug-resistant Enterobacterales, but little data are available on the… read more here.
Keywords: colistin resistant; colistin; resistance; following travel ... See more keywords
Evaluation and readout optimization of the rapid polymyxin NP test for the detection of colistin-resistant Enterobacteriaceae.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001030
Abstract: PURPOSE In an increasing number of cases the last therapeutic option for treatment of carbapenem-resistant Enterobacteriaceae is colistin. As the detection of colistin resistance is problematic and time-consuming, it is desirable to find a rapid… read more here.
Keywords: colistin; polymyxin test; rapid polymyxin; colistin resistant ... See more keywords
In vitro activity of methylene blue and eosin methylene blue agar on colistin-resistant A. baumannii: an experimental study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001078
Abstract: Introduction. Colistin is a last-resort antibiotic used against carbapenem-resistant Acinetobacter baumannii (AB); however, colistin resistance has been reported recently. Methylene blue (MB) is used in microbiology for staining, and in medicine as an antidote drug.Aim.… read more here.
Keywords: agar; colistin; methylene blue; microbiology ... See more keywords
Longitudinal study on the occurrence in pigs of colistin‐resistant Escherichia coli carrying mcr‐1 following the cessation of use of colistin
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Microbiology"
DOI: 10.1111/jam.13907
Abstract: In 2015, colistin‐resistant Escherichia coli and Salmonella with the mcr‐1 gene were isolated from a pig farm in Great Britain. Pigs were subsequently monitored over a ~20‐month period for the occurrence of mcr‐1‐mediated colistin resistance… read more here.
Keywords: escherichia coli; resistant escherichia; colistin resistant; occurrence ... See more keywords