MLN3126, an antagonist of the chemokine receptor CCR9, ameliorates inflammation in a T cell mediated mouse colitis model
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.04.049
Abstract: ABSTRACT C‐C chemokine receptor 9 (CCR9) is the homing receptor for C‐C motif chemokine ligand 25 (CCL25), and contributes to the maintenance of mucosal immunity and pathogenesis of inflammatory bowel disease (IBD) through the recruitment… read more here.
Keywords: mln3126; colitis model; colitis; ccr9 ... See more keywords
Vitamin C Enema Advances Induction of Remission in the Dextran Sodium Sulfate-Induced Colitis Model in Rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of nutritional science and vitaminology"
DOI: 10.3177/jnsv.67.91
Abstract: The current main treatment for ulcerative colitis (UC) is induction therapy by long-term administration of 5-aminosalicylic acid (5-ASA), but various side effects have been reported. Therefore, a radical cure for UC is desired. A vitamin… read more here.
Keywords: induction remission; induction; solution; colitis model ... See more keywords
Recovery of Ischemic Limb and Femoral Artery Endothelial Function Are Preserved in Mice with Dextran Sodium Sulfate-Induced Chronic Colitis
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11081169
Abstract: Simple Summary The present study examines the effect of experimental inflammatory bowel disease on femoral artery endothelial function and limb ischemia recovery in female mice using a chronic colitis model induced by dextran sodium sulfate… read more here.
Keywords: limb; femoral artery; colitis; colitis model ... See more keywords
Therapeutic Potential of Quercetin Loaded Nanoparticles: Novel Insights in Alleviating Colitis in an Experimental DSS Induced Colitis Model
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10071654
Abstract: Oxidative stress is considered the main etiologic factor involved in inflammatory bowel disease (IBD). Integration of nanocarriers for natural therapeutic agents with antioxidant and anti-inflammatory potential is a novel promising candidate for curing IBD. Herein,… read more here.
Keywords: colitis; dss induced; induced colitis; colitis model ... See more keywords