Decreased expression of MUC2 due to a decrease in the expression of lectins and apoptotic defects in colitis patients
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2019.100655
Abstract: Introduction The involvement of mucin, lectin, and apoptosis in colitis is still unclear. This study aimed to investigate changes in MUC2 expression, inflammation, and changes in lectin expression in colitis patients. Methods A total of… read more here.
Keywords: colitis; apoptotic defects; expression; decreased expression ... See more keywords
The prevalence and transcriptional activity of the mucosal microbiota of ulcerative colitis patients
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-35243-4
Abstract: Active microbes likely have larger impact on gut health status compared to inactive or dormant microbes. We investigate the composition of active and total mucosal microbiota of treatment-naïve ulcerative colitis (UC) patients to determine the… read more here.
Keywords: transcriptional activity; colitis patients; ulcerative colitis; mucosal microbiota ... See more keywords
Single Cell Transcriptional Survey of Ileal-Anal Pouch Immune Cells from Ulcerative Colitis Patients.
Sign Up to like & getrecommendations! Published in 2020 at "Gastroenterology"
DOI: 10.1053/j.gastro.2020.12.030
Abstract: BACKGROUND & AIMS Restorative proctocolectomy with ileal pouch-anal anastomosis is a surgical procedure in patients with ulcerative colitis refractory to medical therapies. Pouchitis, the most common complication, is inflammation of the pouch of unknown etiology.… read more here.
Keywords: single cell; immune; pouchitis; colitis ... See more keywords
Tofacitinib Inhibits Leukocyte Trafficking Across the Intestinal Endothelial Barrier in a Specific Cohort of Ulcerative Colitis Patients.
Sign Up to like & getrecommendations! Published in 2022 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izab349
Abstract: The JAK/STAT inhibitor tofacitinib, recently approved for the treatment of ulcerative colitis, is found to modulate the intestinal endothelial barrier functions in directing the leukocyte adhesion and transmigration in ulcerative colitis patients displaying high levels… read more here.
Keywords: intestinal endothelial; endothelial barrier; colitis patients; colitis ... See more keywords
Etiopathogenesis of Nephrolithiasis in Ulcerative Colitis Patients with the Ileal Pouch Anal Anastomosis
Sign Up to like & getrecommendations! Published in 2017 at "Inflammatory Bowel Diseases"
DOI: 10.1097/mib.0000000000001070
Abstract: Background: Our previous study showed that nephrolithiasis is a common complication in ulcerative colitis patients after ileal pouch anal anastomosis (IPAA). However, the pathogenesis of nephrolithiasis in IPAA patients has not been studied. The aim… read more here.
Keywords: study; nephrolithiasis; ulcerative colitis; calcium ... See more keywords
Mucosal interleukin‐8 expression as a predictor of subsequent relapse in ulcerative colitis patients with Mayo endoscopic subscore 0
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.15813
Abstract: Complete endoscopic mucosal healing is defined as a Mayo endoscopic subscore of 0. Some patients diagnosed with a Mayo endoscopic subscore 0 may present with subsequent clinical relapse. Here, we aimed to demonstrate mucosal cytokine… read more here.
Keywords: mayo endoscopic; relapse ulcerative; colitis patients; endoscopic subscore ... See more keywords
Oral health and salivary function in ulcerative colitis patients
Sign Up to like & getrecommendations! Published in 2020 at "United European Gastroenterology Journal"
DOI: 10.1177/2050640620957138
Abstract: Background Although ulcerative colitis primarily involves the colon, extra-intestinal manifestations are common and oral and dental complaints are no exception. Objective This study aims at evaluating oral and dental health problems and salivary function and… read more here.
Keywords: colitis patients; disease; colitis; ulcerative colitis ... See more keywords
Enriched CD45RA−CD62L+ central memory T and decreased CD3+CD56+ natural killer T lymphocyte subsets in the rectum of ulcerative colitis patients
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/20587384211051982
Abstract: Objectives To investigate the distinctive features of lymphocytes promoting inflammation in ulcerative colitis. Methods We performed flow cytometric analysis of peripheral blood mononuclear cells (PBMCs) and colorectal mucosa lymphocytes in ulcerative colitis patients (n =… read more here.
Keywords: cd3; central memory; colitis patients; colitis ... See more keywords
Long-lasting renal dysfunction following tacrolimus induction therapy in ulcerative colitis patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.21-139
Abstract: Although tacrolimus (TAC) has remarkable effects in ulcerative colitis (UC) patients when given as remission induction therapy, some can develop renal dysfunction during TAC administration, resulting in withdrawal, though related details remain poorly understood. This… read more here.
Keywords: induction therapy; tac; colitis patients; ulcerative colitis ... See more keywords
Composition and diverse differences of intestinal microbiota in ulcerative colitis patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.953962
Abstract: Objective To explore the composition of the intestinal microbiota in ulcerative colitis (UC) patients and to identify differences in the microbiota between patients with active disease and those in remission. Methods Between September 2020 and… read more here.
Keywords: intestinal microbiota; patients active; colitis patients; ulcerative colitis ... See more keywords
Distribution of cytomegalovirus genotypes among ulcerative colitis patients in Okinawa, Japan
Sign Up to like & getrecommendations! Published in 2018 at "Intestinal Research"
DOI: 10.5217/ir.2018.16.1.90
Abstract: Background/Aims To determine the prevalence of glycoprotein B (gB), glycoprotein N (gN), and glycoprotein H (gH) genotypes of human cytomegalovirus (HCMV) superimposed on ulcerative colitis (UC) patients in Japan. Methods Four archived stool samples and… read more here.
Keywords: colitis patients; ulcerative colitis; gene encoding; distribution ... See more keywords