Piper umbellatum L. (Piperaceae): Phytochemical profiles of the hydroethanolic leaf extract and intestinal anti-inflammatory mechanisms on 2,4,6 trinitrobenzene sulfonic acid induced ulcerative colitis in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.112707
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Piper umbellatum L. commonly found in the Amazon, Cerrado and Atlantic rain forest regions of Brazil, leaves are widely used as a traditional medicine to treat gastrointestinal disorders and inflammation, among others diseases.… read more here.
Keywords: anti inflammatory; acid; colitis rats; ulcerative colitis ... See more keywords
Desloratadine via its anti-inflammatory and antioxidative properties ameliorates TNBS-induced experimental colitis in rats
Sign Up to like & getrecommendations! Published in 2024 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2024.2360043
Abstract: Abstract Background Intestinal mucosal immune cells, notably mast cells, are pivotal in ulcerative colitis (UC) pathophysiology. Its activation elevates tissue concentrations of histamine. Inhibiting colonic histamine release could be an effective therapeutic strategy for treating… read more here.
Keywords: colitis rats; tnbs induced; antioxidative properties; anti inflammatory ... See more keywords
Detection of the Content of Two Coumarins, IM and ISOIM, and Their Mechanism of Action on Colitis Rats in Angelica albicans
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/5475559
Abstract: Angelica albicans is being used in the cure of different, respiratory, neuromuscular, and cutaneous diseases in traditional eastern medicine. The pharmacokinetic (PK) characteristics of imperatorin (IM) and isoimperatorin (ISOIM), the main effective components in Angelica… read more here.
Keywords: content two; detection content; colitis rats; angelica albicans ... See more keywords
Non-Adherent Bone Marrow-Derived Mesenchymal Stem Cells Ameliorate Clinical Manifestations and Inflammation in an Experimental Model of Ulcerative Colitis in Rats
Sign Up to like & getrecommendations! Published in 2020 at "Iranian Journal of Medical Sciences"
DOI: 10.30476/ijms.2020.72514.0
Abstract: Background: Functional and developmental versatility of mesenchymal stem cells (MSCs) have generated great interest in their clinical application. Recently, it has been proposed that the non-adherent population of bone marrow cells can differentiate to MSCs… read more here.
Keywords: colitis rats; non adherent; adherent mscs; mscs ... See more keywords
Lycium barbarum polysaccharides and capsaicin modulate inflammatory cytokines and colonic microbiota in colitis rats induced by dextran sulfate sodium
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.21-174
Abstract: Active ingredients in the natural products have been considered to be used for alleviating the symptoms of ulcerative colitis, hence the effects of Lycium barbarum polysaccharides (LP) and capsaicin on dextran sulfate sodium (DSS)-induced colitis… read more here.
Keywords: microbiota; colitis rats; lycium barbarum; colitis ... See more keywords
Mesenteric Lymphatic B Cells Migrate to the Gut and Aggravate TNBS-Induced Rat Colitis via Regulating Intestinal T Cells
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26083519
Abstract: Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is affecting a growing global population. Unlike UC, which is characterized by inflammation confined to the intestinal mucosa and submucosa, CD involves transmural… read more here.
Keywords: colitis rats; intestinal cells; mlb cells; mesenteric lymphatic ... See more keywords
AphaMax®, an Aphanizomenon Flos-Aquae Aqueous Extract, Exerts Intestinal Protective Effects in Experimental Colitis in Rats
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DOI: 10.3390/nu12123635
Abstract: Background: Aphanizomenon flos-aquae (AFA) is a unicellular cyanobacterium considered to be a “superfood” for its complete nutritional profile and beneficial properties. We investigated possible beneficial effects of an AFA extract, commercialized as AphaMax®, containing concentrated… read more here.
Keywords: colitis rats; aphanizomenon flos; flos aquae; treatment ... See more keywords
Isoimperatorin alleviates acetic acid–induced colitis in rats
Sign Up to like & getrecommendations! Published in 2024 at "Asian Pacific Journal of Tropical Biomedicine"
DOI: 10.4103/apjtb.apjtb_851_23
Abstract: To investigate the effect of isoimperatorin on histopathological and biochemical changes in acetic acid-induced colitis rats. Colitis was induced by intracolonic administration of acetic acid solution (4% v/v) in rats. Rats were divided into six… read more here.
Keywords: colitis rats; acid induced; acetic acid; colitis ... See more keywords