Fibrillar Collagen Variants in Spontaneous Coronary Artery Dissection.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.0001
Abstract: Importance Spontaneous coronary artery dissection (SCAD) is an increasingly recognized nonatherosclerotic cause of acute myocardial infarction enriched among individuals with early-onset myocardial infarction but is of unclear etiology. Objective To assess which genes contribute to… read more here.
Keywords: coronary artery; spontaneous coronary; collagen; dissection ... See more keywords
Effect of Intramyocardial Grafting Collagen Scaffold With Mesenchymal Stromal Cells in Patients With Chronic Ischemic Heart Disease
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.16236
Abstract: This randomized clinical trial evaluates the safety and feasibility of a collagen gel vehicle for mesenchymal stromal cell treatment, compared with cell treatment alone and no cell treatment, in patients with chronic ischemic heart disease… read more here.
Keywords: collagen; mesenchymal stromal; heart disease; chronic ischemic ... See more keywords
Structural and biochemical characterization of Clostridium perfringens pili protein B collagen‐binding domains
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14626
Abstract: Sortase‐mediated pili are flexible rod proteins composed of major and minor/tip pilins, playing important roles in the initial adhesion of bacterial cells to host tissues. The pilus shaft is formed by covalent polymerization of major… read more here.
Keywords: collagen; binding domains; tip; clostridium perfringens ... See more keywords
MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13440
Abstract: Fibrillar collagen deposition, stiffness and downstream signalling support the development of leiomyomas (LMs), common benign mesenchymal tumours of the uterus, and are associated with aggressiveness in multiple carcinomas. Compared to epithelial carcinomas, however, the impact… read more here.
Keywords: expression collagen; uterine leiomyosarcoma; collagen; support ... See more keywords
The durability of resin–dentine bonds are enhanced by epigallocatechin‐3‐gallate‐encapsulated nanohydroxyapatite/mesoporous silica
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13521
Abstract: Biomimetic nanohydroxyapatite (nHAp) has long been used as a biocompatible material for bone repair, bone regeneration, and bone reconstruction due to its low toxicity to local or systemic tissues. Various cross‐linkers have been employed to… read more here.
Keywords: nhap msn; egcg; egcg nhap; collagen ... See more keywords
Collagen Stiffness and Architecture Regulate Fibrotic Gene Expression in Engineered Adipose Tissue
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Biosystems"
DOI: 10.1002/adbi.201900286
Abstract: Adipose tissue (AT) has a dynamic extracellular matrix (ECM) surrounding adipocytes that allows for remodeling during metabolic fluctuations. During the progression of obesity, AT has increased ECM deposition, stiffening, and remodeling, resulting in a pro‐fibrotic… read more here.
Keywords: collagen; stiffness architecture; expression; gene expression ... See more keywords
Self-assembled Hydrogel Fiber Bundles from Oppositely Charged Polyelectrolytes Mimic Micro-/nanoscale Hierarchy of Collagen.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced functional materials"
DOI: 10.1002/adfm.201606273
Abstract: Fiber bundles are present in many tissues throughout the body. In most cases, collagen subunits spontaneously self-assemble into a fibrilar structure that provides ductility to bone and constitutes the basis of muscle contraction. Translating these… read more here.
Keywords: collagen; fiber bundles; self assembled; hydrogel fiber ... See more keywords
Multiphasic Collagen Scaffolds for Engineered Tissue Interfaces
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201804730
Abstract: Hard–soft tissue interfaces pose unique challenges for regeneration due to architectural, mechanical, and compositional changes between tissues, which are difficult to incorporate into tissue engineering scaffolds. Multiphasic scaffolds are needed to better mimic structural and… read more here.
Keywords: collagen; tissue interfaces; scaffolds engineered; collagen scaffolds ... See more keywords
An Intrinsically Nontrimerizing Peptide Probe for Specifically Targeting Pathological Collagen in Connective Tissues
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202004532
Abstract: The efficient detection of pathological collagen plays an essential role in the diagnosis, prognosis, and treatment of various critical diseases such as arthritis and tumors. Peptide probes with the (Gly‐Pro‐Hyp)n sequences have been recently discovered… read more here.
Keywords: nontrimerizing peptide; collagen; pathological collagen; intrinsically nontrimerizing ... See more keywords
Combined Methylglyoxal Scavenger and Collagen Hydrogel Therapy Prevents Adverse Remodeling and Improves Cardiac Function Post‐Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202108630
Abstract: Methylglyoxal (MG) is a highly reactive dicarbonyl and the main precursor of advanced glycation end‐products (AGEs). After myocardial infarction (MI), MG‐derived AGEs accumulate in the heart and contribute to adverse remodeling and loss of cardiac… read more here.
Keywords: cardiac function; collagen; function; therapy ... See more keywords
Biomanufacturing Seamless Tubular and Hollow Collagen Scaffolds with Unique Design Features and Biomechanical Properties.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201601136
Abstract: A versatile process to develop designer collagen scaffolds for hollow and tubular tissue engineering applications is presented. This process creates seamless and biomechanically tunable scaffolds ranging from ureter-like microsized tubings to structures with highly customized… read more here.
Keywords: collagen; seamless tubular; hollow collagen; collagen scaffolds ... See more keywords