Control of osteoblast arrangement by osteocyte mechanoresponse through prostaglandin E2 signaling under oscillatory fluid flow stimuli.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.121203
Abstract: Anisotropic collagen/apatite microstructure is a prominent determinant of bone tissue functionalization; in particular, bone matrix modulates its anisotropic microstructure depending on the surrounding mechanical condition. Although mechanotransduction in bones is governed by osteocyte function, the… read more here.
Keywords: bone matrix; bone; osteoblast arrangement; flow stimuli ... See more keywords
Analysis of Bone Regeneration Based on the Relationship between the Orientations of Collagen and Apatite in Mouse Femur
Sign Up to like & getrecommendations! Published in 2020 at "Materials Transactions"
DOI: 10.2320/matertrans.mt-m2019341
Abstract: In this study, we focused on the preferential orientation of the extracellular matrix (ECM) of bone, since ECM orientation has been shown to significantly affect the mechanical functions of bones. Bone analysis is in most… read more here.
Keywords: collagen; bone regeneration; bone; mouse femur ... See more keywords
A Novel Ex Vivo Bone Culture Model for Regulation of Collagen/Apatite Preferential Orientation by Mechanical Loading
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137423
Abstract: The anisotropic microstructure of bone, composed of collagen fibers and biological apatite crystallites, is an important determinant of its mechanical properties. Recent studies have revealed that the preferential orientation of collagen/apatite composites is closely related… read more here.
Keywords: vivo bone; mechanical loading; collagen; collagen apatite ... See more keywords