Infrared attenuated total reflection spectroscopic surface analysis of bovine-tail intervertebral discs after UV-light-activated riboflavin-induced collagen crosslinking.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biophotonics"
DOI: 10.1002/jbio.202000110
Abstract: The tensile strength of the intervertebral disc (IVD) is mainly maintained by collagen cross-links. Loss of collagen cross-linking combined with other age-related degenerative processes contributes to tissue weakening, biomechanical failure, disc herniation and pain. Exogenous… read more here.
Keywords: collagen; bovine; infrared attenuated; attenuated total ... See more keywords
Glycosylated CD147 reduces myocardial collagen cross‐linking in cardiac hypertrophy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26713
Abstract: The mechanism of transition from chronic pressure overload‐induced cardiac hypertrophy to heart failure is still unclear. Angiotensin II (Ang II) may be an important factor that mediates the transition in the end‐stage of cardiac hypertrophy.… read more here.
Keywords: cardiac hypertrophy; hypertrophy; cross linking; collagen cross ... See more keywords
Transepithelial accelerated corneal collagen cross-linking with higher oxygen availability for keratoconus: 1-year results
Sign Up to like & getrecommendations! Published in 2017 at "International Ophthalmology"
DOI: 10.1007/s10792-017-0762-5
Abstract: PurposeTo investigate the safety and efficacy of a new protocol for transepithelial accelerated corneal collagen cross-linking with higher oxygen availability for keratoconus treatment.MethodsThere were 26 patients (26 eyes) diagnosed with keratoconus enrolled in the study… read more here.
Keywords: cross linking; corneal collagen; collagen cross; accelerated corneal ... See more keywords
Simultaneous photorefractive keratectomy and accelerated collagen cross-linking in high-risk refractive surgery (Tehran protocol): 3-year outcomes
Sign Up to like & getrecommendations! Published in 2020 at "International Ophthalmology"
DOI: 10.1007/s10792-020-01447-9
Abstract: Purpose To evaluate safety and efficacy of performing simultaneous photorefractive keratectomy (PRK) and collagen cross-linking (CXL) in myopic patients with preoperative risk factors for developing keratectasia. Methods Seventeen eyes of 15 patients with at least… read more here.
Keywords: photorefractive keratectomy; log mar; risk; simultaneous photorefractive ... See more keywords
Evaluation of Iontophoretic Collagen Cross-linking for Early Stage of Progressive Keratoconus Compared to Standard Cross-linking: A Non-Inferiority Study
Sign Up to like & getrecommendations! Published in 2017 at "Ophthalmology and Therapy"
DOI: 10.1007/s40123-017-0076-8
Abstract: IntroductionThe purpose of this study was to evaluate the efficacy and safety of iontophoretic collagen cross-linking (I-CXL) compared to epithelium-off standard collagen cross-linking (CXL) in treating the early stages of progressive keratoconus.MethodsThis retrospective cohort study… read more here.
Keywords: cross; collagen cross; cxl group; cross linking ... See more keywords
Current methods of collagen cross-linking: Review.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.06.075
Abstract: This review provides a report on cross-linking methods used for collagen modifications. Collagen materials have attracted significant academic interest due to its biological properties in native state. However, in many cases the mechanical properties and… read more here.
Keywords: cross; linking methods; review; collagen cross ... See more keywords
Response to “Comment on: Effectiveness and safety of accelerated (9 mW/cm2) corneal collagen cross-linking for progressive keratoconus: a 24-month follow-up”
Sign Up to like & getrecommendations! Published in 2019 at "Eye"
DOI: 10.1038/s41433-019-0371-9
Abstract: We thank Dr. De Bernardo et al. for their interest and their insightful comments on our recently published paper on accelerated corneal collagen cross-linking (CXL) for progressive keratoconus [1]. We fully agree that, instead of… read more here.
Keywords: corneal; progressive keratoconus; study; corneal thickness ... See more keywords
FKBP65-dependent peptidyl-prolyl isomerase activity potentiates the lysyl hydroxylase 2-driven collagen cross-link switch
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep46021
Abstract: Bruck Syndrome is a connective tissue disease associated with inactivating mutations in lysyl hydroxylase 2 (LH2/PLOD2) or FK506 binding protein 65 (FKBP65/FKBP10). However, the functional relationship between LH2 and FKBP65 remains unclear. Here, we postulated… read more here.
Keywords: collagen; peptidyl prolyl; lysyl hydroxylase; collagen cross ... See more keywords
Collagen cross-linking mediated by lysyl hydroxylase 2: an enzymatic battlefield to combat fibrosis.
Sign Up to like & getrecommendations! Published in 2019 at "Essays in biochemistry"
DOI: 10.1042/ebc20180051
Abstract: The hallmark of fibrosis is an excessive accumulation of collagen, ultimately leading to organ failure. It has become evident that the deposited collagen also exhibits qualitative modifications. A marked modification is the increased cross-linking, leading… read more here.
Keywords: cross linking; collagen cross; fibrosis; cross ... See more keywords
Severe Complications after Corneal Collagen Cross-Linking (CXL)
Sign Up to like & getrecommendations! Published in 2022 at "Klinische Monatsblatter Fur Augenheilkunde"
DOI: 10.1055/a-2040-4290
Abstract: Abstract Purpose To present a case series of rare and severe complications after corneal collagen cross-linking (CXL) of keratoconus patients. Methods Single-center descriptive case series covering the period of 2012 to 2022 at the Department… read more here.
Keywords: corneal collagen; collagen cross; severe complications; patient ... See more keywords
Predictive Factors for Corneal Scarring in Progressive Keratoconus Patients after Corneal Collagen Cross-linking.
Sign Up to like & getrecommendations! Published in 2021 at "Ophthalmic epidemiology"
DOI: 10.1080/09286586.2021.1883677
Abstract: Objectives : To evaluate predictive factors for corneal scar formation following corneal collagen cross-linking (CXL). Methods : The medical records of 295 progressive keratoconus patients who had undergone accelerated CXL were reviewed retrospectively in this… read more here.
Keywords: predictive factors; collagen cross; cross linking; factors corneal ... See more keywords