Circulating markers of collagen types I, III, and IV in patients with dilated cardiomyopathy: relationships with myocardial collagen expression
Sign Up to like & getrecommendations! Published in 2018 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12360
Abstract: Collagen‐derived peptides such as collagen I C‐terminal telopeptide (CITP) and procollagen III N‐terminal propeptide (PIIINP) have been conventionally used as markers of cardiac fibrosis. Collagen IV 7S domain (P4NP 7S) has been recently reported to… read more here.
Keywords: collagen; markers collagen; myocardial collagen; collagen expression ... See more keywords
Captopril mitigates splenomegaly and myelofibrosis in the Gata1 low murine model of myelofibrosis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13710
Abstract: Allogeneic stem cell transplantation is currently the only curative therapy for primary myelofibrosis (MF), while the JAK2 inhibitor, ruxolitinib. Has been approved only for palliation. Other therapies are desperately needed to reverse life‐threatening MF. However,… read more here.
Keywords: myelofibrosis; model; collagen expression; mitigates splenomegaly ... See more keywords
Pterostilbene and Its Glucoside Induce Type XVII Collagen Expression
Sign Up to like & getrecommendations! Published in 2017 at "Natural Product Communications"
DOI: 10.1177/1934578x1701200123
Abstract: The glycosylation of pterostilbene by cultured plant cells of Phytolacca americana gave pterostilbene 4′-O-β-D-glucoside. Both pterostilbene and its 4-O-β-D-glucoside induced type XVII collagen expression in the EpiDermFT EFT-400 human skin cell model. Pterostilbene 4′-O-β-D-glucoside strongly… read more here.
Keywords: pterostilbene glucoside; xvii collagen; type xvii; collagen expression ... See more keywords
Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.791376
Abstract: Objective: Osteoarthritis (OA) is a common disease with a complex pathology including mechanical load, inflammation, and metabolic factors. Chondrocyte ferroptosis contributes to OA progression. Because iron deposition is a major pathological event in ferroptosis, deferoxamine… read more here.
Keywords: chondrocyte ferroptosis; ferroptosis; dfo; collagen expression ... See more keywords
Phosphatidylethanolamine Induces an Antifibrotic Phenotype in Normal Human Lung Fibroblasts and Ameliorates Bleomycin-Induced Lung Fibrosis in Mice
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19092758
Abstract: Lung surfactant is a complex mixture of phospholipids and specific proteins but its role in the pathogenesis of interstitial lung diseases is not established. Herein, we analyzed the effects of three representative phospholipid components, that… read more here.
Keywords: bleomycin induced; lung fibrosis; collagen expression; lung ... See more keywords