Dimorphic Mechanisms of Fragility in Diabetes Mellitus: the Role of Reduced Collagen Fibril Deformation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4706
Abstract: Diabetes mellitus (DM) is an emerging metabolic disease, and the management of diabetic bone disease poses a serious challenge worldwide. Understanding the underlying mechanisms leading to high fracture risk in DM is hence of particular… read more here.
Keywords: deformation; advanced glycation; bone; collagen fibril ... See more keywords
Modeling the effect of collagen fibril alignment on ligament mechanical behavior
Sign Up to like & getrecommendations! Published in 2018 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-017-0977-4
Abstract: Ligament mechanical behavior is primarily regulated by fibrous networks of type I collagen. Although these fibrous networks are typically highly aligned, healthy and injured ligament can also exhibit disorganized collagen architecture. The objective of this… read more here.
Keywords: collagen; ligament; mechanical behavior; collagen fibril ... See more keywords
Cell regulation of collagen fibril macrostructure during corneal morphogenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.08.017
Abstract: While tissue form and function is highly dependent upon tissue-specific collagen composition and organization, little is known of the mechanisms controlling the bundling of collagen fibrils into fibers and larger structural designs that lead to… read more here.
Keywords: collagen; corneal; collagen fibril; fibril macrostructure ... See more keywords
Collagen fibril abnormalities in human and mice abdominal aortic aneurysm.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.04.022
Abstract: Vascular diseases like abdominal aortic aneurysms (AAA) are characterized by a drastic remodeling of the vessel wall, accompanied with changes in the elastin and collagen content. At the macromolecular level, the elastin fibers in AAA… read more here.
Keywords: collagen; collagen fibrils; microscopy; collagen fibril ... See more keywords
Percolation networks inside 3D model of the mineralized collagen fibril
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-90916-x
Abstract: Bone is a hierarchical biological material, characterized at the nanoscale by a recurring structure mainly composed of apatite mineral and collagen, i.e. the mineralized collagen fibril (MCF). Although the architecture of the MCF was extensively… read more here.
Keywords: collagen; mineralized collagen; percolation; collagen fibril ... See more keywords
The Effect of the Wooden Breast Fibrotic Myopathy in Broilers on Fibrillar Collagen Organization and Decorin-Collagen Binding
Sign Up to like & getrecommendations! Published in 2018 at "Avian Diseases"
DOI: 10.1637/11985-102218-reg.1
Abstract: SUMMARY. The wooden breast myopathy is identified by the palpation of a rigid pectoralis major muscle and results in myofiber necrosis and fibrosis in fast-growing, meat-type broilers. The fibrosis in wooden breast–affected muscle is characterized… read more here.
Keywords: collagen; line; collagen fibril; decorin ... See more keywords