Collagen fibril abnormalities in human and mice abdominal aortic aneurysm.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.04.022
Abstract: Vascular diseases like abdominal aortic aneurysms (AAA) are characterized by a drastic remodeling of the vessel wall, accompanied with changes in the elastin and collagen content. At the macromolecular level, the elastin fibers in AAA… read more here.
Keywords: collagen; collagen fibrils; microscopy; collagen fibril ... See more keywords
Tropocollagen springs allow collagen fibrils to stretch elastically.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2022.01.041
Abstract: The mechanical properties of connective tissues are tailored to their specific function, and changes can lead to dysfunction and pathology. In most mammalian tissues the mechanical environment is governed by the micro- and nano-scale structure… read more here.
Keywords: collagen; tissue; spring; pathology ... See more keywords
Understanding the Molecular Mechanism of Cation Permeation in the Cardiac Ryanodine Receptor (RyR2) Channel using Computational Electrophysiology
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2017.11.665
Abstract: 582-Pos Board B352 Strained Collagen Resists Bacterial Collagenase Degradation Karanvir Saini, Manorama Tiwari, Jerome Irianto, Charlotte Pfeifer, Cory Alvey, Dennis E. Discher. Univ of Pennsylvania, Univ of Pennsylvania, Philadelphia, PA, USA. Background: Collagen, a triple-helical,… read more here.
Keywords: collagen; collagen fibrils; mechanical strain; strain ... See more keywords
Fucosylated chondroitin sulfate is covalently associated with collagen fibrils in sea cucumber Apostichopus japonicus body wall.
Sign Up to like & getrecommendations! Published in 2018 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2018.01.041
Abstract: Fucosylated chondroitin sulfate (fCS) is the major carbohydrate constituent of sea cucumber. However, the distribution of fCS in the sea cucumber body wall has not been fully described. We addressed this in the present study… read more here.
Keywords: collagen fibrils; body wall; sea cucumber; fucosylated chondroitin ... See more keywords
Action of trypsin on structural changes of collagen fibres from sea cucumber (Stichopus japonicus).
Sign Up to like & getrecommendations! Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2018.02.117
Abstract: Trypsin, a representative serine proteinase, was used to hydrolyse the collagen fibres from sea cucumber (Stichopus japonicus) to highlight the role of serine proteinase in the autolysis of sea cucumber. Partial disaggregation of collagen fibres… read more here.
Keywords: collagen; collagen fibrils; fibres sea; collagen fibres ... See more keywords
Collagen fibrils of sea cucumber (Apostichopus japonicus) are heterotypic.
Sign Up to like & getrecommendations! Published in 2020 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.126272
Abstract: Sea cucumbers attracted increasing interest due to its nutritional functions. Collagen is the most important structural biomacromolecule in sea cucumber body wall, and is highly related to the textual properties and food quality of sea… read more here.
Keywords: collagen; apostichopus japonicus; collagen fibrils; sea cucumber ... See more keywords
Flavonoids determine the rate of fibrillogenesis and structure of collagen type I fibrils in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.06.070
Abstract: Collagen fibrils are produced from collagen monomers not only in vivo, but also in vitro. The ability to have an influence on the structure and properties of fibrils may find medical application and can be… read more here.
Keywords: collagen; collagen fibrils; formation collagen; formation ... See more keywords
Disintegration of collagen fibrils by Glucono-δ-lactone: An implied lead for disintegration of fibrosis.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.08.158
Abstract: Excess accumulation of collagen (fibrosis) undergoes self-aggregation, which leads to fibrillar collagen, on the extracellular matrix is the hallmark of a number of diseases such as keloids, hypertrophic scars, and systemic scleroderma. Direct inhibition or… read more here.
Keywords: collagen; collagen fibrils; disintegration collagen; anti fibrotic ... See more keywords
MMP-9 selectively cleaves non-D-banded material on collagen fibrils with discrete plasticity damage in mechanically-overloaded tendon.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2019.03.020
Abstract: The mechanical properties of tendon are due to the properties and arrangement of its collagen fibril content. Collagen fibrils are highly-organized supermolecular structures with a periodic banding pattern (D-band) indicative of the geometry of molecular… read more here.
Keywords: collagen; collagen fibrils; discrete plasticity; damage ... See more keywords
Ultrastructural response of tendon to excessive level or duration of tensile load supports that collagen fibrils are mechanically continuous.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2019.05.002
Abstract: The basic collagen fibril structure of tendons continues to be debated in the literature. Some studies have proposed that collagen fibrils are longitudinally discontinuous, with the load-bearing ability of tendon dependent on interfibrillar shear strength.… read more here.
Keywords: collagen; load; collagen fibrils; response tendon ... See more keywords
Microstructure dependent binding of pigment epithelium derived factor (PEDF) to type I collagen fibrils.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2017.06.001
Abstract: Pigment epithelium derived factor (PEDF) is a multifunctional extracellular protein. In addition to its known anti-angiogenic and neurotrophic roles in collagen rich tissues, PEDF is thought to be involved in collagen fibril assembly due to… read more here.
Keywords: collagen; collagen fibrils; epithelium derived; pedf ... See more keywords