P278 Type IV collagen formation/degradation ratio predicts response to infliximab induction therapy in patients with Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjab076.403
Abstract: Up to 50% of patients with ulcerative colitis (UC) do not respond to biological therapies, including TNF-α-antagonists (e.g., infliximab, IFX) and migration inhibitors (e.g., the α4β7-integrin inhibitor vedolizumab, VEDO). Therefore, serological biomarkers that predict therapy… read more here.
Keywords: colitis; therapy; response; formation degradation ... See more keywords
MiR-142 and miR-212 synergistically inhibits the proliferation and collagen formation of TGF-β1-induced cardiac fibroblasts by regulating c-Myc/TP53INP1.
Sign Up to like & getrecommendations! Published in 2020 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2019-0495
Abstract: OBJECTIVE To investigate the effect and mechanism of miR-142-5p/212-5p on the proliferation and collagen formation of cardiac fibroblasts (CFs). METHODS The mouse MI model was established by ligation of the left anterior descending coronary artery.… read more here.
Keywords: collagen formation; 142 212; mir 142; proliferation ... See more keywords
miR-30a-5p inhibits the proliferation and collagen formation of cardiac fibroblasts in diabetic cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2022 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2021-0280
Abstract: Cardiac fibrosis is one of the major pathological characteristics of diabetic cardiomyopathy (DCM). MicroRNAs (miRNAs, miRs) have been identified as key regulators in the progression of cardiac fibrosis. This study aimed to investigate the role… read more here.
Keywords: mir 30a; diabetic cardiomyopathy; collagen formation; proliferation ... See more keywords