Protective effect of lupeol on arthritis induced by type II collagen via the suppression of P13K/AKT signaling pathway in Sprague dawley rats.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental toxicology"
DOI: 10.1002/tox.23529
Abstract: To explore the therapeutic value of lupeol on collagen-induced arthritis (CIA) in rats, a rheumatoid arthritis model. Lupeol is well known pentacyclic triterpene found in various plant sources, which possess anti-inflammatory and antioxidant actions. The… read more here.
Keywords: p13k akt; lupeol; arthritis; akt signaling ... See more keywords
A novel fusion protein attenuates collagen–induced arthritis by targeting interleukin 17A and tumor necrosis factor &agr;
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.05.058
Abstract: Graphical abstract Figure. No caption available. ABSTRACT This study was undertaken to generate a novel dual targeting fusion protein (DTF), targeting tumor necrosis factor &agr; (TNF‐&agr;) and interleukin 17A (IL‐17A), and determine its anti‐arthritis properties… read more here.
Keywords: interleukin 17a; collagen induced; tumor necrosis; factor agr ... See more keywords
Celastrol attenuates collagen-induced arthritis via inhibiting oxidative stress in rats.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106527
Abstract: The present work aimed to investigate the anti-rheumatism effect and the mechanism of celastrol in collagen-induced arthritis (CIA) rats. The CIA model was established in male Wistar rats by intradermal injection of bovine collagen-II in… read more here.
Keywords: induced arthritis; cia rats; celastrol; collagen induced ... See more keywords
Autologous collagen-induced chondrogenesis versus microfracture for chondral defects of the knee: Surgical technique and 2-year comparison outcome study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of orthopaedics"
DOI: 10.1016/j.jor.2020.06.008
Abstract: Objective Osteochondral lesions of the knee affect patients from all age groups with arthroscopic microfracture being the current gold standard of treatment of such lesions. Autologous collagen-induced chondrogenesis (ACIC) is a novel procedure that has… read more here.
Keywords: chondral defects; microfracture; collagen induced; autologous collagen ... See more keywords
Anti-arthritic effect of pentosan polysulfate in rats with collagen-induced arthritis.
Sign Up to like & getrecommendations! Published in 2019 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2018.11.028
Abstract: Pentosan polysulfate (PPS) is currently under investigation as a potential disease-modifying antiarthritic agent. In the present study the effects of PPS on arthritic profiles based on clinical score, ankle size, histological changes, and activity of… read more here.
Keywords: induced arthritis; anti arthritic; arthritic rats; collagen induced ... See more keywords
Cyclic Citrullinated Peptide Aptamer Treatment Attenuates Collagen-Induced Arthritis.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00144
Abstract: We describe the study of a novel aptamer-based candidate for treatment of seropositive rheumatoid arthritis. The candidate is a nanoparticle-formulated cyclic citrullinated peptide aptamer, which targets autoantibodies and/or the immune reactions leading to antibody production.… read more here.
Keywords: aptamer; peptide aptamer; citrullinated peptide; treatment ... See more keywords
Atractylodin Suppresses Dendritic Cell Maturation and Ameliorates Collagen-Induced Arthritis in a Mouse Model.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b01163
Abstract: The aim of this study was to evaluate the immunomodulatory effects of atractylodin, a polyethylene alkyne, on the maturation of bone marrow-derived dendritic cells (BM-DC) as well as its antirheumatic effect on collagen-induced arthritis (CIA)… read more here.
Keywords: induced arthritis; model; collagen induced; maturation ... See more keywords
Zerumbone Protects Rats from Collagen-Induced Arthritis by Inhibiting Oxidative Outbursts and Inflammatory Cytokine Levels
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c05749
Abstract: Rheumatoid arthritis (RA) is an immunocompromised disorder characterized by a marked increase in the synthesis of inflammatory molecules that stimulates the destruction of bones and cartilage. The conventional treatment modalities for RA are associated with… read more here.
Keywords: induced arthritis; collagen induced; zerumbone protects; inflammatory cytokine ... See more keywords
Therapeutic effects of matrine derivate MASM in mice with collagen-induced arthritis and on fibroblast-like synoviocytes
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-02423-7
Abstract: MASM is a matrine derivate that exhibits a number of pharmacological effects, including immunosuppressive activity and anti-inflammatory properties. In this study, the mechanisms underlying the therapeutic efficacy of MASM in the treatment of rheumatoid arthritis… read more here.
Keywords: induced arthritis; masm; mice collagen; collagen induced ... See more keywords
The preventive effects of nanopowdered red ginseng on collagen-induced arthritic mice
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Food Sciences and Nutrition"
DOI: 10.1080/09637486.2017.1358359
Abstract: Abstract This study was carried out to investigate the efficiency of red ginseng nanopowder in preventing collagen-induced arthritis (CIA) in mice. The mice were divided into five groups: normal group (no immunisation), control (CIA), powdered… read more here.
Keywords: red ginseng; collagen induced; group; nanopowdered red ... See more keywords
Alteration of the gut microbiota in tumor necrosis factor‐α antagonist‐treated collagen‐induced arthritis mice
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.13802
Abstract: Gut microbiota play an important role in rheumatoid arthritis (RA). Biological therapies targeting tumor necrosis factor‐α (TNF‐α) have been used for treatment in RA patients. However, whether TNF‐α antagonist has some influence on gut microbiota… read more here.
Keywords: necrosis factor; tumor necrosis; induced arthritis; gut microbiota ... See more keywords