To achieve self‐assembled collagen mimetic fibrils using designed peptides
Sign Up to like & getrecommendations! Published in 2018 at "Biopolymers"
DOI: 10.1002/bip.23226
Abstract: It has proven challenging to obtain collagen‐mimetic fibrils by protein design. We recently reported the self‐assembly of a mini‐fibril showing a 35 nm, D‐period like, axially repeating structure using the designed triple helix Col108. Peptide… read more here.
Keywords: using designed; collagen mimetic; self; mini fibrils ... See more keywords
Covalent Capture of a Collagen Mimetic Peptide with an Integrin-Binding Motif.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00155
Abstract: Collagen mimetic peptides (CMPs) are an excellent model to study the structural and biological properties of the extracellular matrix (ECM) due to ease of synthesis and variability in sequence. To ensure that synthetic materials accurately… read more here.
Keywords: covalent capture; integrin binding; peptide; collagen mimetic ... See more keywords
Inviting C5-Trifluoromethylated Pseudoprolines into Collagen Mimetic Peptides.
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01242
Abstract: Numerous collagen mimetic peptides (CMPs) have been engineered using proline derivatives substituted at their C(3) and/or C(4) position in order to stabilize or functionalize collagen triple-helix mimics. However, no example has been reported so far… read more here.
Keywords: triple helix; inviting trifluoromethylated; mimetic peptides; collagen mimetic ... See more keywords
A self-assembling collagen mimetic peptide system to simultaneously characterize the effects of osteogenesis imperfecta mutations on conformation, assembly and activity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Chemistry B"
DOI: 10.1039/c9tb00086k
Abstract: We have created a self-assembling collagen mimetic peptide system which for the first time facilitates simultaneous characterization of the effects of osteogenesis imperfecta mutations on stability, conformation, assembly and activity. read more here.
Keywords: assembling collagen; peptide system; collagen mimetic; effects osteogenesis ... See more keywords
Combining simulations and experiments for the molecular engineering of multifunctional collagen mimetic peptide-based materials.
Sign Up to like & getrecommendations! Published in 2021 at "Soft matter"
DOI: 10.1039/d0sm01562h
Abstract: Assembling peptides allow the creation of structurally complex materials, where amino acid selection influences resulting properties. We present a synergistic approach of experiments and simulations for examining the influence of natural and non-natural amino acid… read more here.
Keywords: reactive handle; inclusion; cmp triple; multifunctional collagen ... See more keywords
Collagen Mimetic Peptides
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineering"
DOI: 10.3390/bioengineering8010005
Abstract: Since their first synthesis in the late 1960s, collagen mimetic peptides (CMPs) have been used as a molecular tool to study collagen, and as an approach to develop novel collagen mimetic biomaterials. Collagen, a major… read more here.
Keywords: collagen; collagen mimetic; mimetic peptides;
Supramolecular Nanofibers from Collagen-Mimetic Peptides Bearing Various Aromatic Groups at N-Termini via Hierarchical Self-Assembly
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22094533
Abstract: Self-assembly of artificial peptides has been widely studied for constructing nanostructured materials, with numerous potential applications in the nanobiotechnology field. Herein, we report the synthesis and hierarchical self-assembly of collagen-mimetic peptides (CMPs) bearing various aromatic… read more here.
Keywords: mimetic peptides; self assembly; bearing various; collagen mimetic ... See more keywords