Image-based Characterization of 3D Collagen Networks and the Effect of Embedded Cells
Sign Up to like & getrecommendations! Published in 2019 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927619014570
Abstract: Abstract Collagen microstructure is closely related to the mechanical properties of tissues and affects cell migration through the extracellular matrix. To study these structures, three-dimensional (3D) in vitro collagen-based gels are often used, attempting to… read more here.
Keywords: collagen networks; microscopy; image based; collagen fibers ... See more keywords
Compressive Remodeling Alters Fluid Transport Properties of Collagen Networks – Implications for Tumor Growth
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-50268-z
Abstract: Biomechanical alterations to the tumor microenvironment include accumulation of solid stresses, extracellular matrix (ECM) stiffening and increased fluid pressure in both interstitial and peri-tumoral spaces. The relationship between interstitial fluid pressurization and ECM remodeling in… read more here.
Keywords: collagen networks; tumor growth; compressive remodeling; growth ... See more keywords
Collective Cell Migration on Collagen-I Networks: The Impact of Matrix Viscoelasticity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.901026
Abstract: Collective cell migration on extracellular matrix (ECM) networks is a key biological process involved in development, tissue homeostasis and diseases such as metastatic cancer. During invasion of epithelial cancers, cell clusters migrate through the surrounding… read more here.
Keywords: cell; rheology; cell migration; collagen networks ... See more keywords