MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness.
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DOI: 10.1002/1878-0261.13440
Abstract: Fibrillar collagen deposition, stiffness and downstream signalling support the development of leiomyomas (LMs), common benign mesenchymal tumours of the uterus, and are associated with aggressiveness in multiple carcinomas. Compared to epithelial carcinomas, however, the impact… read more here.
Keywords: expression collagen; uterine leiomyosarcoma; collagen; support ... See more keywords
Cause or consequence? Identification of collagen remodelling in striae
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DOI: 10.1111/bjd.16259
Abstract: patients with PPP, several exceptions have been reported, suggesting the existence of modifier mutations. M€ ossner et al. sought to investigate these issues through the analysis of an extended disease cohort including 61 patients with… read more here.
Keywords: cause consequence; remodelling striae; collagen remodelling; identification collagen ... See more keywords
Collagen remodelling and plasma ascorbic acid levels in patients suspected of inherited bleeding disorders harbouring germline variants in collagen‐related genes
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DOI: 10.1111/hae.14195
Abstract: Variants in collagen‐related genes COL1A1, COL3A1, COL5A1 and COL5A2 are associated with Ehlers‐Danlos syndrome (EDS), a heterogeneous group of connective tissue disorders strongly associated with increased bleeding. Of patients with incompletely explained bleeding diathesis, a… read more here.
Keywords: collagen; collagen related; collagen remodelling; variants collagen ... See more keywords