Maltodextrin/ascorbic acid stimulates wound closure by increasing collagen turnover and TGF-β1 expression in vitro and changing the stage of inflammation from chronic to acute in vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of tissue viability"
DOI: 10.1016/j.jtv.2017.01.004
Abstract: It has been reported that carbohydrates confer physicochemical properties to the wound environment that improves tissue repair. We evaluated in vitro and in vivo wound healing during maltodextrin/ascorbic acid treatment. In a fibroblast monolayer scratch assay, we… read more here.
Keywords: maltodextrin ascorbic; collagen turnover; ascorbic acid;
A Targeted Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Quantification of Peptides from the Carboxyl-terminal Region of Type III Procollagen, Biomarkers of Collagen Turnover.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical chemistry"
DOI: 10.1093/clinchem/hvac119
Abstract: BACKGROUND The development of analytical approaches to help reduce the risk of growth hormone (GH) doping is important to fair competition and the health of athletes. However, the reliable detection of GH use remains challenging.… read more here.
Keywords: collagen turnover; iii; targeted liquid; type iii ... See more keywords
Increased Collagen Turnover Is a Feature of Fibromuscular Dysplasia and Associated With Hypertrophic Radial Remodeling: A Pilot, Urine Proteomic Study
Sign Up to like & getrecommendations! Published in 2021 at "Hypertension"
DOI: 10.1161/hypertensionaha.121.18146
Abstract: Supplemental Digital Content is available in the text. Fibromuscular dysplasia (FMD), a nonatherosclerotic, noninflammatory disease of medium-sized arteries, is an underdiagnosed disease. We investigated the urinary proteome and developed a classifier for discrimination of FMD… read more here.
Keywords: study; patients fmd; disease; collagen turnover ... See more keywords
Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0194458
Abstract: The extracellular matrix (ECM) plays a vital role in maintaining normal tissue function. Collagens are major components of the ECM and there is a tight equilibrium between degradation and formation of these proteins ensuring tissue… read more here.
Keywords: collagen; age; matrix; sex ... See more keywords
Biomarkers of collagen turnover and wound healing in chronic thromboembolic pulmonary hypertension patients before and after pulmonary endarterectomy.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of cardiology"
DOI: 10.2139/ssrn.4325929
Abstract: BACKGROUND In chronic thromboembolic pulmonary hypertension (CTEPH), fibrotic remodeling of tissue and thrombi contributes to disease progression. Removal of the thromboembolic mass by pulmonary endarterectomy (PEA) improves hemodynamics and right ventricular function, but the roles… read more here.
Keywords: wound healing; biomarkers collagen; collagen turnover; chronic thromboembolic ... See more keywords
Role of collagen turnover biomarkers in the noninvasive assessment of myocardial fibrosis: an update.
Sign Up to like & getrecommendations! Published in 2020 at "Biomarkers in medicine"
DOI: 10.2217/bmm-2020-0298
Abstract: The pro-fibrotic milieu, as the result of the extracellular matrix remodeling, is a central feature in the pathophysiology of heart disease and contributes to its high morbidity and mortality. Fibrosis is a recognized risk factor… read more here.
Keywords: collagen; fibrosis; collagen turnover; turnover biomarkers ... See more keywords
HIF1A inhibitor PX-478 reduces pathological stretch-induced calcification and collagen turnover in aortic valve
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1002067
Abstract: HIF1A is significantly upregulated in calcified human aortic valves (AVs). Furthermore, HIF1A inhibitor PX-478 was shown to inhibit AV calcification under static and disturbed flow conditions. Since elevated stretch is one of the major mechanical… read more here.
Keywords: calcification; stretch; inhibitor 478; collagen turnover ... See more keywords
The Role of Circulating Collagen Turnover Biomarkers and Late Gadolinium Enhancement in Patients with Non-Ischemic Dilated Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12061435
Abstract: Background: Myocardial scarring is a primary pathogenetic process in nonischemic dilated cardiomyopathy (NIDCM) that is responsible for progressive cardiac remodeling and heart failure, severely impacting the survival of these patients. Although several collagen turnover biomarkers… read more here.
Keywords: collagen turnover; late gadolinium; turnover biomarkers; dilated cardiomyopathy ... See more keywords