Articles with "collateral dependencies" as a keyword



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Analysis of Cancer Genomic Amplifications Identifies Druggable Collateral Dependencies within the Amplicon

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers15061636

Abstract: The identification of novel therapeutic targets for specific cancer molecular subtypes is crucial for the development of precision oncology. In the last years, CRISPR/Cas9 screens have accelerated the discovery and validation of new targets associated… read more here.

Keywords: genomic amplifications; dependencies within; collateral dependencies; cancer genomic ... See more keywords