Genes Vary Greatly in Their Propensity for Collateral Fitness Effects of Mutations
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DOI: 10.1093/molbev/msad038
Abstract: Mutations can have deleterious fitness effects when they decrease protein specific activity or decrease active protein abundance. Mutations will also be deleterious when they cause misfolding or misinteractions that are toxic to the cell (i.e.,… read more here.
Keywords: vary greatly; genes vary; fitness effects; collateral fitness ... See more keywords