Characterisation of the spectrum and genetic dependence of collateral mutations induced by translesion DNA synthesis
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DOI: 10.1371/journal.pgen.1010051
Abstract: Translesion DNA synthesis (TLS) is a fundamental damage bypass pathway that utilises specialised polymerases with relaxed template specificity to achieve replication through damaged DNA. Misinsertions by low fidelity TLS polymerases may introduce additional mutations on… read more here.
Keywords: translesion dna; collateral; collateral mutations; dna synthesis ... See more keywords