Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage
Sign Up to like & getrecommendations! Published in 2017 at "Nature Microbiology"
DOI: 10.1038/nmicrobiol.2016.268
Abstract: Host control of infections crucially depends on the capability to kill pathogens with reactive oxygen species (ROS). However, these toxic molecules can also readily damage host components and cause severe immunopathology. Here, we show that… read more here.
Keywords: myeloperoxidase; salmonella; host; damage ... See more keywords
Liquid biopsy reveals collateral tissue damage in cancer
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.153559
Abstract: Cancer inflicts damage to surrounding normal tissues, which can culminate in fatal organ failure. Here, we demonstrate that cell death in organs affected by cancer can be detected by tissue-specific methylation patterns of circulating cell-free… read more here.
Keywords: damage; collateral tissue; damage cancer; tissue damage ... See more keywords
Immune Resolution Dilemma: Host Antimicrobial Factor S100A8/A9 Modulates Inflammatory Collateral Tissue Damage During Disseminated Fungal Peritonitis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.553911
Abstract: Intra-abdominal infection (peritonitis) is a leading cause of severe disease in surgical intensive care units, as over 70% of patients diagnosed with peritonitis develop septic shock. A critical role of the immune system is to… read more here.
Keywords: tissue damage; collateral tissue; s100a8; mice ... See more keywords