Directional Collective Migration in Wound Healing Assays.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7701-7_2
Abstract: Cell migration is suppressed by confluence in a process called contact inhibition. Relieving contact inhibition upon scratching is one of the simplest ways to induce cell migration in a variety of cell types. Wound healing… read more here.
Keywords: wound healing; directional collective; migration; collective migration ... See more keywords
To lead or to herd: optimal strategies for 3D collective migration of cell clusters.
Sign Up to like & getrecommendations! Published in 2020 at "Biomechanics and modeling in mechanobiology"
DOI: 10.1007/s10237-020-01290-y
Abstract: Cells migrating in clusters play a significant role in a number of biological processes such as embryogenesis, wound healing, and tumor metastasis during cancer progression. A variety of environmental and biochemical factors can influence the… read more here.
Keywords: cell clusters; cell migration; migration; collective migration ... See more keywords
Swarming and collective migration of micromotors under near infrared light
Sign Up to like & getrecommendations! Published in 2018 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2018.08.004
Abstract: Abstract It is nowadays of a great challenge to create and navigate artificial micro/nanomotor swarms by external stimuli, which, however, may develop reconfigurable robots or programmable matter for cooperative grasping, collective cargo transportation, microfactories, etc.… read more here.
Keywords: near infrared; convection; collective migration; motor ... See more keywords
Hypoxia, partial EMT and collective migration: Emerging culprits in metastasis
Sign Up to like & getrecommendations! Published in 2020 at "Translational Oncology"
DOI: 10.1016/j.tranon.2020.100845
Abstract: Epithelial-mesenchymal transition (EMT) is a cellular biological process involved in migration of primary cancer cells to secondary sites facilitating metastasis. Besides, EMT also confers properties such as stemness, drug resistance and immune evasion which can… read more here.
Keywords: emt; partial emt; metastasis; collective migration ... See more keywords
A Rho-GTPase based model explains spontaneous collective migration of neural crest cell clusters.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.01.013
Abstract: We propose a model to explain the spontaneous collective migration of neural crest cells in the absence of an external gradient of chemoattractants. The model is based on the dynamical interaction between Rac1 and RhoA… read more here.
Keywords: spontaneous collective; model; migration; collective migration ... See more keywords
Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-05578-7
Abstract: Epithelial sheet spreading is a fundamental cellular process that must be coordinated with cell division and differentiation to restore tissue integrity. Here we use consecutive serum deprivation and re-stimulation to reconstruct biphasic collective migration and… read more here.
Keywords: coordinated collective; cell division; migration; collective migration ... See more keywords
Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22940-3
Abstract: In this article, we explore a non-canonical form of collective cell migration, displayed by the metastatic murine mammary carcinoma cell line 4T1. We show here that in sparsely plated 4T1 cells, E-cadherin levels are moderately… read more here.
Keywords: mammary carcinoma; migration; collective migration; role ... See more keywords
Azobenzene-based sinusoidal surface topography drives focal adhesion confinement and guides collective migration of epithelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71567-w
Abstract: Surface topography is a key parameter in regulating the morphology and behavior of single cells. At multicellular level, coordinated cell displacements drive many biological events such as embryonic morphogenesis. However, the effect of surface topography… read more here.
Keywords: topography; focal adhesion; surface; collective migration ... See more keywords
Polarization of ADAM17‐driven EGFR signalling in electric field‐guided collective migration of epidermal sheets
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16019
Abstract: Endogenous electric field is considered to play an important role in promoting collective migration of epidermis to the wound centre. However, most studies are focused on the effect of bioelectric field on the movement and… read more here.
Keywords: egfr signalling; migration; migration epidermal; collective migration ... See more keywords
The microenvironment induces collective migration in SDHB-silenced mouse pheochromocytoma spheroids.
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine-related cancer"
DOI: 10.1530/erc-17-0212
Abstract: Pheochromocytomas (Pheos) and paragangliomas (PGLs) are neuroendocrine tumors. Approximately 30-40% of Pheos/PGLs are due to germline mutations in one of the susceptibility genes, including those encoding the succinate dehydrogenase subunits A-D (SDHA-D). Up to 2/3… read more here.
Keywords: microenvironment; sdhb silenced; migration sdhb; migration ... See more keywords
MACC1-Induced Collective Migration Is Promoted by Proliferation Rather Than Single Cell Biomechanics
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14122857
Abstract: Simple Summary High metastasis-associated in colon cancer 1 (MACC1) expression is associated with metastasis, tumor cell migration, and increased proliferation in colorectal cancer. Tumors with high MACC1 expression show a worse prognosis and higher invasion… read more here.
Keywords: cell; collective migration; proliferation; single cell ... See more keywords