Colletofragarone A2 Inhibits Cancer Cell Growth In Vivo and Leads to the Degradation and Aggregation of Mutant p53.
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DOI: 10.1021/acs.chemrestox.2c00202
Abstract: Mutant p53 not only loses its original tumor suppressor function but also acquires new abilities regarding oncogenic progression. Therefore, the strategy of targeting mutant p53 has attracted attention for cancer therapy. We isolated colletofragarone A2… read more here.
Keywords: colletofragarone; mutant p53; cell growth; growth vivo ... See more keywords