Articles with "collies homozygous" as a keyword



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Tolerance and Pharmacokinetics of Galliprant™ Administered Orally to Collies Homozygous for MDR1-1Δ.

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Published in 2021 at "Journal of veterinary pharmacology and therapeutics"

DOI: 10.1111/jvp.12984

Abstract: The objectives of the study were to evaluate the pharmacokinetics and tolerance of grapiprant, a substrate of the human P-gp transporter, in collies homozygous for MDR1-1Δ when administered at the labeled dosage of 2 mg/kg once… read more here.

Keywords: tolerance pharmacokinetics; collies homozygous; homozygous mdr1; pharmacokinetics galliprant ... See more keywords