Association of Distance, Region, and Insurance With Advanced Colon Cancer at Initial Diagnosis
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.29954
Abstract: This cross-sectional study examines factors associated with the stage at which colon cancer is diagnosed. read more here.
Keywords: region insurance; colon cancer; distance region; association distance ... See more keywords
ARL2 is required for homologous recombination repair and colon cancer stem cell survival
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13438
Abstract: ARL2 regulates the dynamics of cytological components and is highly expressed in colon cancer tissues. Here, we report novel roles of ARL2 in the cell nucleus and colon cancer stem cells (CSCs). ARL2 is expressed… read more here.
Keywords: arl2; cancer stem; colon cancer; colon ... See more keywords
A Bioprinted Tubular Intestine Model using a Colon-Specific Extracellular Matrix Bioink.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101768
Abstract: Tremendous advances have been made toward accurate recapitulation of the human intestinal system in vitro to understand its developmental process, and disease progression. However, current in vitro models are often confined to 2D or 2.5D… read more here.
Keywords: extracellular matrix; tissue; colon; model ... See more keywords
IL-36γ and IL-36Ra Reciprocally Regulate Colon Inflammation and Tumorigenesis by Modulating the Cell-Matrix Adhesion Network and Wnt Signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202103035
Abstract: Inflammatory bowel disease and colorectal cancer are associated with dysregulation of cytokine networks. However, it is challenging to target cytokines for effective intervention because of the overlapping functions and unpredictable interactions of cytokines in such… read more here.
Keywords: cell matrix; matrix adhesion; reciprocally regulate; tumorigenesis ... See more keywords
Identification of a novel colon adenocarcinoma cell targeting peptide using phage display library biopanning
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DOI: 10.1002/bab.2320
Abstract: Phage display is well recognized as a promising high‐throughput screening tool for the discovery of novel cancer‐targeting peptides. Here, we screened a phage display library of 7‐mer random peptides through in vitro biopanning to isolate… read more here.
Keywords: display library; cell; phage display; colon ... See more keywords
Running course of the colon during the embryonic period
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Anatomy"
DOI: 10.1002/ca.23469
Abstract: Cho et al. (2018) recently described the topographical anatomy of the intestine during the embryonic stage using sagittal histological sections (Clinical Anatomy 31:583–592, 2018). Strikingly, out of 17 samples, 11 “abnormal” samples were found with… read more here.
Keywords: limb; anatomy; period; tract ... See more keywords
BRD9 is an essential regulator of glycolysis that creates an epigenetic vulnerability in colon adenocarcinoma
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DOI: 10.1002/cam4.4954
Abstract: The intensive interplay between aberrant epigenetic events and metabolic remodeling represents one of the hallmarks of tumors, including colon cancer. The functions of Bromodomain Containing Protein BRD‐9 in colon cancer remains indefinite. We aimed to… read more here.
Keywords: essential regulator; brd9 essential; regulator glycolysis; colon cancer ... See more keywords
The efficiency of neoadjuvant chemotherapy in colon cancer with mismatch repair deficiency
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DOI: 10.1002/cam4.5076
Abstract: Colon cancers with mismatch repair deficiency (dMMR) have specific clinicopathologic characteristics compared with mismatch repair proficiency (pMMR); however, the effect of MMR status on the efficiency of neoadjuvant chemotherapy (NCT) remains unclear. In our study,… read more here.
Keywords: neoadjuvant chemotherapy; mismatch repair; colon cancer; cancer ... See more keywords
Effects of SMC1A on immune microenvironment and cancer stem cells in colon adenocarcinoma.
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DOI: 10.1002/cam4.5891
Abstract: BACKGROUND Our previous study suggested that SMC1 has significant functions in colorectal cancer (CRC). However, few reports have shown the effects of structural maintenance of chromosomes 1 (SMC1A) on the immune microenvironment and tumor stem… read more here.
Keywords: cell; smc1a; stem cells; cancer ... See more keywords
Multi-omic analysis in normal colon organoids highlights MSH4 as a novel marker of defective mismatch repair in Lynch syndrome and microsatellite instability.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6048
Abstract: INTRODUCTION Lynch syndrome (LS) is a hereditary condition that increases the risk of colorectal (CRC) and extracolonic cancers that exhibit microsatellite instability (MSI-H). MSI-H is driven by defective mismatch repair (dMMR), and approximately 15% of… read more here.
Keywords: normal colon; expression; colon organoids; lynch syndrome ... See more keywords
Study Links Surgical Skills to Fewer Long‐Term Colon Cancer Complications
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DOI: 10.1002/cncr.33605
Abstract: P atients with colorectal cancer whose operations were performed by more technically skilled surgeons were 70% more likely to survive long term, according to a study by Northwestern University researchers published in JAMA Surgery.1 The… read more here.
Keywords: surgical skills; study; colon; bilimoria ... See more keywords