Articles with "colon" as a keyword



Association of Distance, Region, and Insurance With Advanced Colon Cancer at Initial Diagnosis

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Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.29954

Abstract: This cross-sectional study examines factors associated with the stage at which colon cancer is diagnosed. read more here.

Keywords: region insurance; colon cancer; distance region; association distance ... See more keywords

Variance Decomposition of Racial and Ethnic Disparities in Colon Cancer.

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Published in 2024 at "JAMA surgery"

DOI: 10.1001/jamasurg.2024.0424

Abstract: This cohort study examines the hospital factors associated with disparities in access and quality of colon cancer care among Hispanic patients. read more here.

Keywords: decomposition racial; colon; variance decomposition; racial ethnic ... See more keywords

Validated Integration of Tumor Deposits in N Staging for Prognostication in Colon Cancer.

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Published in 2025 at "JAMA surgery"

DOI: 10.1001/jamasurg.2024.6729

Abstract: Importance Tumor deposits have prognostic value in colon cancer, but the current American Joint Committee on Cancer (AJCC) staging only considers them if there are no concurrent positive lymph nodes. Objective To devise a staging… read more here.

Keywords: cancer; sassun mayo; colon; tumor deposits ... See more keywords

MMP‐9‐dependent proteolysis of the histone H3 N‐terminal tail: a critical epigenetic step in driving oncogenic transcription and colon tumorigenesis

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Published in 2024 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13652

Abstract: Matrix metalloproteinase 9 (MMP‐9) is a member of the MMP family and has been recently identified as a nuclear protease capable of clipping histone H3 N‐terminal tails (H3NT). This MMP‐9‐dependent H3NT proteolysis is critical for… read more here.

Keywords: mmp; proteolysis; mmp dependent; colon ... See more keywords

ARL2 is required for homologous recombination repair and colon cancer stem cell survival

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Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13438

Abstract: ARL2 regulates the dynamics of cytological components and is highly expressed in colon cancer tissues. Here, we report novel roles of ARL2 in the cell nucleus and colon cancer stem cells (CSCs). ARL2 is expressed… read more here.

Keywords: arl2; cancer stem; colon cancer; colon ... See more keywords

A Bioprinted Tubular Intestine Model using a Colon-Specific Extracellular Matrix Bioink.

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Published in 2021 at "Advanced healthcare materials"

DOI: 10.1002/adhm.202101768

Abstract: Tremendous advances have been made toward accurate recapitulation of the human intestinal system in vitro to understand its developmental process, and disease progression. However, current in vitro models are often confined to 2D or 2.5D… read more here.

Keywords: extracellular matrix; tissue; colon; model ... See more keywords

A Sustained H2/Fluorouracil‐Releasing Suppository for High‐efficacy and Low‐Toxicity Hydrogenochemotherapy of Colon Cancer

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Published in 2025 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202404054

Abstract: To attenuate the intestinal toxicity of chemotherapeutic drugs from rectal suppositories and enhance their chemotherapeutic outcome is greatly significant, but maintains a challenge. In this work, a new strategy of local synergistic hydrogenochemotherapy is proposed… read more here.

Keywords: cancer; suppository high; colon; toxicity ... See more keywords

Colon‐Targeted Ginseng Polysaccharides‐Based Microspheres for Improving Ulcerative Colitis via Anti‐Inflammation and Gut Microbiota Modulation

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Published in 2025 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202404122

Abstract: Natural plant‐derived polysaccharides exhibit substantial potential for treating ulcerative colitis (UC) owing to their anti‐inflammatory and antioxidant properties and favorable safety profiles. However, their practical application faces several challenges, including structural instability in gastric acid,… read more here.

Keywords: ginseng polysaccharides; gut microbiota; colon; ulcerative colitis ... See more keywords

IL-36γ and IL-36Ra Reciprocally Regulate Colon Inflammation and Tumorigenesis by Modulating the Cell-Matrix Adhesion Network and Wnt Signaling.

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Published in 2022 at "Advanced science"

DOI: 10.1002/advs.202103035

Abstract: Inflammatory bowel disease and colorectal cancer are associated with dysregulation of cytokine networks. However, it is challenging to target cytokines for effective intervention because of the overlapping functions and unpredictable interactions of cytokines in such… read more here.

Keywords: cell matrix; matrix adhesion; reciprocally regulate; tumorigenesis ... See more keywords

Identification of a novel colon adenocarcinoma cell targeting peptide using phage display library biopanning

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Published in 2022 at "Biotechnology and Applied Biochemistry"

DOI: 10.1002/bab.2320

Abstract: Phage display is well recognized as a promising high‐throughput screening tool for the discovery of novel cancer‐targeting peptides. Here, we screened a phage display library of 7‐mer random peptides through in vitro biopanning to isolate… read more here.

Keywords: display library; cell; phage display; colon ... See more keywords

Running course of the colon during the embryonic period

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Published in 2019 at "Clinical Anatomy"

DOI: 10.1002/ca.23469

Abstract: Cho et al. (2018) recently described the topographical anatomy of the intestine during the embryonic stage using sagittal histological sections (Clinical Anatomy 31:583–592, 2018). Strikingly, out of 17 samples, 11 “abnormal” samples were found with… read more here.

Keywords: limb; anatomy; period; tract ... See more keywords