Protective Effect of Lactobacillus casei on DMH-Induced Colon Carcinogenesis in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-017-9253-2
Abstract: The administration of probiotics is a promising approach to reduce the prevalence of colon cancer, a multifactorial disease, with hereditary factors, as well as environmental lifestyle-related risk factors. Biogenic polyamines, putrescine, spermidine, and spermine are… read more here.
Keywords: lactobacillus casei; colon carcinogenesis; ornithine decarboxylase; colon ... See more keywords
Preventive potential of dietary inclusion of Brachystegia eurycoma (Harms) seeds on N-methyl-N-nitrosourea-induced colon carcinogenesis in Wistar rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.111858
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Brachystegia eurycoma seed is used as dietary condiment and as part of recipes for treating colorectal disorders, while laboratory studies have established that it contains crude fiber and polyphenols which are important in… read more here.
Keywords: seed; colon carcinogenesis; brachystegia eurycoma; eurycoma ... See more keywords
The Protective Role of Urtica dioica Seed Extract Against Azoxymethane-Induced Colon Carcinogenesis in Rats.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition and cancer"
DOI: 10.1080/01635581.2021.1881568
Abstract: The aim of this study was to investigate the protective role of Urtica dioica seed (UDS) extract against azoxymethane (AOM)-induced colon carcinogenesis in rats. Thirty-two male Wistar albino rats were divided into four groups: Control,… read more here.
Keywords: seed; aom uds; colon carcinogenesis; colon ... See more keywords
Synergistic chemopreventive effects of nobiletin and atorvastatin on colon carcinogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Carcinogenesis"
DOI: 10.1093/carcin/bgx018
Abstract: Different cancer chemopreventive agents may act synergistically and their combination may produce enhanced protective effects against carcinogenesis than each individual agent alone. Herein, we investigated the chemopreventive effects of nobiletin (NBT, a citrus polymethoxyflavone) and… read more here.
Keywords: cancer; nbt atst; colon carcinogenesis; colon ... See more keywords
Sphingosine Kinase 1 expression in peritoneal macrophages is required for colon carcinogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Carcinogenesis"
DOI: 10.1093/carcin/bgx104
Abstract: Accumulating evidence suggests that the sphingosine kinase 1 (SphK1)/sphingosine 1-phosphate (S1P) pathway plays a pivotal role in colon carcinogenesis. Our previous studies indicate that the SphK1/S1P pathway mediates colon carcinogenesis at least by regulating cyclooxygenase… read more here.
Keywords: peritoneal macrophages; expression; colon carcinogenesis; colon ... See more keywords
The chemopreventive effect of withaferin A on spontaneous and inflammation-associated colon carcinogenesis models
Sign Up to like & getrecommendations! Published in 2018 at "Carcinogenesis"
DOI: 10.1093/carcin/bgy109
Abstract: Chemopreventive effects and associated mechanisms of withaferin A (WA) against intestinal and colon carcinogenesis remain unknown. We investigated the chemopreventive effect of WA on transgenic adenomatous polyposis coli (APCMin/+) mouse and chemically induced azoxymethane/dextran sodium… read more here.
Keywords: colon carcinogenesis; colon; chemopreventive effect; aom dss ... See more keywords
Biochemical and molecular aspects of 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis: a review.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology research"
DOI: 10.1093/toxres/tfaa004
Abstract: 1,2-dimethylhydrazine (DMH) is a member in the class of hydrazines, strong DNA alkylating agent, naturally present in cycads. DMH is widely used as a carcinogen to induce colon cancer in animal models. Exploration of DMH-induced… read more here.
Keywords: induced colon; dmh induced; colon carcinogenesis; colon ... See more keywords
Evaluation of the preventive potential of graded dietary inclusion of Hyphaene thebaica (Linn) fruit in rat model of colon carcinogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14446
Abstract: The preventive effect of Hyphaene thebaica fruit in colon carcinogenesis was evaluated in Wistar rats at 0, 2.5, 5 and 10% inclusion rates for twelve weeks with concomitant 72-h intra-rectal N-methyl-N-nitrosourea (MNU) instillations. Indices of… read more here.
Keywords: hyphaene thebaica; colon carcinogenesis; fruit;
Dietary Tricin Suppresses Inflammation-Related Colon Carcinogenesis in Mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of nutritional science and vitaminology"
DOI: 10.3177/jnsv.65.s100
Abstract: Tricin present in rice and wheat exhibits antigrowth activity in several human cancer cell lines and anti-inflammatory potential. However, the chemopreventive activity has not yet been elucidated in preclinical animal models. This study was designed… read more here.
Keywords: colon carcinogenesis; inflammation; tricin; mice ... See more keywords
Targeting Gut Microbial Biofilms—A Key to Hinder Colon Carcinogenesis?
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12082272
Abstract: Colorectal cancer (CRC) is a global public health issue which poses a substantial humanistic and economic burden on patients, healthcare systems and society. In recent years, intestinal dysbiosis has been suggested to be involved in… read more here.
Keywords: colon carcinogenesis; colon; hinder colon; gut microbial ... See more keywords
Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23116292
Abstract: Colorectal cancer (CRC) is one of most common cancers worldwide, with high rates of mortality. Epidemiological findings demonstrate that coffee consumption reduces the risk of developing CRC by ~13%. In general, in vivo and in… read more here.
Keywords: coffee; early stage; mir 21a; colon carcinogenesis ... See more keywords