Breadfruit flavonoid derivatives attenuate advanced glycation end products (AGEs)-enhanced colon malignancy in HCT116 cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.01.050
Abstract: Abstract Advanced glycation end products (AGEs)-evoked response is an important event in colon tumorigenesis. The aim of this study was to investigate the effect of flavonoid derivatives isolated from breadfruit Artocarpus communis on AGEs-enhanced colon… read more here.
Keywords: age; enhanced colon; colon malignancy; colon ... See more keywords
Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007687
Abstract: The transcription factor Oct1/Pou2f1 promotes poised gene expression states, mitotic stability, glycolytic metabolism and other characteristics of stem cell potency. To determine the effect of Oct1 loss on stem cell maintenance and malignancy, we deleted… read more here.
Keywords: oct1 pou2f1; colon; malignancy; colon malignancy ... See more keywords