Intestinal Sulfation is Essential to Protect Against Colitis and Colonic Carcinogenesis.
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DOI: 10.1053/j.gastro.2021.03.048
Abstract: BACKGROUND & AIMS Sulfation is a conjugation reaction essential for numerous biochemical and cellular functions in mammals. The 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase 2 (PAPSS2) is the key enzyme to generate PAPS, which is the universal… read more here.
Keywords: colonic carcinogenesis; papss2; sulfation; colitis colonic ... See more keywords
Are Corrupted Non-dysplastic Colonic Crypts the First Histological Event in Experimental Colonic Carcinogenesis?
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DOI: 10.21873/anticanres.11563
Abstract: BACKGROUND The colonic crypts in rats replicate by symmetric fission at the base of the crypts, and proceeds upwards, to generate two separate identical crypts. Recently, anomalous crypts (called corrupted colonic crypts, CCCs) were found… read more here.
Keywords: colonic crypts; cccs; non dysplastic; colonic carcinogenesis ... See more keywords