Selective stimulation of colonic L cells improves metabolic outcomes in mice
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DOI: 10.1007/s00125-020-05149-w
Abstract: Aims/hypothesis Insulin-like peptide-5 (INSL5) is found only in distal colonic L cells, which co-express glucagon-like peptide-1 (GLP-1) and peptide YY (PYY). GLP-1 is a well-known insulin secretagogue, and GLP-1 and PYY are anorexigenic, whereas INSL5… read more here.
Keywords: stimulation; food intake; distal colonic; selective stimulation ... See more keywords