Kaempferol Inhibits Colonic Contractions via L‑Type Voltage-Dependent Calcium Channels in Murine Smooth Muscle Cells
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DOI: 10.1021/acsomega.5c03615
Abstract: Kaempferol, a natural flavonoid in various herbs, exhibits many therapeutical effects of anti-inflammation, antitumor, antioxidation, and so on. While its therapeutic potential has been established in many diseases, Kaempferol’s side effect on colonic motility and… read more here.
Keywords: muscle; kaempferol; type; calcium ... See more keywords
Propulsive colonic contractions are mediated by inhibition-driven poststimulus responses that originate in interstitial cells of Cajal.
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123020119
Abstract: SignificanceThe peristaltic reflex elicits colonic migrating motor complexes (CMMCs) that are thought to be generated by enteric excitatory neurons stimulating smooth muscle cells (SMCs). We found that atropine did not block CMMCs and present a… read more here.
Keywords: colonic contractions; interstitial cells; contractions mediated; propulsive colonic ... See more keywords