Chemometric and computational modeling of polysaccharide coated drugs for colonic drug delivery
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DOI: 10.1038/s41598-025-99823-x
Abstract: A methodology based on Principal Component Analysis (PCA) and machine learning (ML) regression was developed in this study for predicting 5-aminosalicylic acid drug release from polysaccharide-coated formulation. The Raman method was used for collection of… read more here.
Keywords: polysaccharide coated; colonic drug; release; drug delivery ... See more keywords
Development of Polymeric-Based Formulation as Potential Smart Colonic Drug Delivery System
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DOI: 10.3390/polym14173697
Abstract: Conventional oral formulations are mainly absorbed in the small intestine. This limits their use in the treatment of some diseases associated with the colon, where the drug has to act topically at the inflammation site.… read more here.
Keywords: system; delivery system; drug delivery; drug ... See more keywords