Multi-color Molecular Visualization of Signaling Proteins Reveals How C-Terminal Src Kinase Nanoclusters Regulate T Cell Receptor Activation.
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DOI: 10.1016/j.celrep.2020.108523
Abstract: Elucidating the mechanisms that controlled TÂ cell activation requires visualization of the spatial organization of multiple proteins on the submicron scale. Here, we use stoichiometrically accurate, multiplexed, single-molecule super-resolution microscopy (DNA-PAINT) to image the nanoscale spatial… read more here.
Keywords: molecular visualization; color molecular; multi color; activation ... See more keywords