NICD3 regulates the expression of MUC5AC and MUC2 by recruiting SMARCA4 and is involved in the differentiation of mucinous colorectal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13296
Abstract: Adenocarcinoma is the most prevalent histological subtype of colorectal cancer (CRC), with mucinous colorectal adenocarcinoma (MCA) being a unique form. Although the mucinous subtype is known to elicit a worse response to chemotherapy and immunotherapy… read more here.
Keywords: colorectal adenocarcinoma; mucinous colorectal; crc; muc5ac muc2 ... See more keywords
Prognosis of three histological subtypes of colorectal adenocarcinoma: A retrospective analysis of 8005 Chinese patients
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2234
Abstract: To evaluate the effect of the varied histological subtypes on clinical outcomes and to determine the prognostic implications of mucinous adenocarcinomas (MAC) and signet ring cell carcinomas (SRCC) compared with classic adenocarcinomas (AC). read more here.
Keywords: subtypes colorectal; histological subtypes; prognosis three; three histological ... See more keywords
Colorectal adenocarcinoma‐derived EGFR mutants are oncogenic and sensitive to EGFR‐targeted monoclonal antibodies, cetuximab and panitumumab
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32499
Abstract: Somatic mutations of epidermal growth factor receptor (EGFR) occur in ~3% of colorectal cancer (CRC) patients. Here, through systematic functional screening of 21 recurrent EGFR mutations selected from public data sets, we show that 11… read more here.
Keywords: derived egfr; egfr; egfr mutants; adenocarcinoma derived ... See more keywords
Melatonin increases the effect of 5-fluorouracil-based chemotherapy in human colorectal adenocarcinoma cells in vitro
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-017-3154-2
Abstract: Melatonin has antitumor activity via several mechanisms including its anti-proliferative and pro-apoptotic effects. Moreover, it has been proven that melatonin in combination with chemotherapeutic agents enhances chemotherapy-triggered apoptosis in several types of cancer. Therefore, this… read more here.
Keywords: human colorectal; melatonin increases; melatonin; adenocarcinoma cells ... See more keywords
An Unusual Case of Colorectal Adenocarcinoma Presenting as an Anterior Mediastinal Mass
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Colorectal Cancer"
DOI: 10.1016/j.clcc.2017.10.009
Abstract: Introduction Colorectal cancer is the second leading cause of cancer-related death in the United States when both genders are combined, but in Puerto Rico is the leading cause of cancer-related death. Puerto Rican men and… read more here.
Keywords: anterior mediastinal; case; mediastinal mass; cancer ... See more keywords
Photo-induced eradication of human colorectal adenocarcinoma HT-29 cells by carbon monoxide (CO) delivery from a Mn-based green luminescent photoCORM
Sign Up to like & getrecommendations! Published in 2019 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2018.09.088
Abstract: Abstract Exogenous CO delivery to cellular targets for salutary purposes can be readily achieved with photoactive metal carbonyl complexes (photoCORMs). Mn(I)-based photoCORMs are often favored for their ability to release CO upon triggering with visible… read more here.
Keywords: colorectal adenocarcinoma; luminescent photocorm; adenocarcinoma cells; human colorectal ... See more keywords
Intussuscepted Metachronous small bowel tumor after treatment for colorectal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2019.05.008
Abstract: Highlights • We present a case of a small bowel adenocarcinoma at an advanced stage, following surgery and adjuvant therapy for colorectal adenocarcinoma, with an atypical presentation at the emergency room, as a rare cause… read more here.
Keywords: small bowel; bowel; colorectal adenocarcinoma; bowel tumor ... See more keywords
A serine protease extracted from Trichosanthes kirilowii inhibits epithelial-mesenchymal transition via antagonizing PKM2-mediated STAT3/Snail1 pathway in human colorectal adenocarcinoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.12.001
Abstract: Abstract Trichosanthes kirilowii extract possessed various medicinal functions. Recently, it was reported that a serine protease TKP isolated from T. kirilowii inhibits human colorectal adenocarcinoma cell proliferation through inducing apoptosis. In the present study, we… read more here.
Keywords: pkm2; stat3 snail1; human colorectal; adenocarcinoma cells ... See more keywords
The relationship between p53, Bcl2 proteins and histological grade in colorectal adenocarcinoma associated with type 2 diabetes and obesity
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the Nutrition Society"
DOI: 10.1017/s0029665120005753
Abstract: Abstract Introduction The aim of our study was to evaluate the expression of p53 protein in colorectal adenocarcinoma in diabetic (type 2) obese vs non-obese vs and to analyse p53, Bcl2 proteins expression in type… read more here.
Keywords: diabetic patients; colorectal adenocarcinoma; grade; bcl2 ... See more keywords
Flat colorectal adenocarcinoma: a worrisome false negative of artificial intelligence-assisted colonoscopy.
Sign Up to like & getrecommendations! Published in 2022 at "Endoscopy"
DOI: 10.1055/a-1738-9632
Abstract: The development of artificial intelligence (AI) systems in the field of colorectal endoscopy is currently booming, colorectal cancer being, by its frequency and severity, a serious public health concern. In terms of image analysis, AI… read more here.
Keywords: colorectal adenocarcinoma; adenocarcinoma worrisome; flat colorectal; artificial intelligence ... See more keywords
CRCBaSe: a Swedish register-based resource for colorectal adenocarcinoma research
Sign Up to like & getrecommendations! Published in 2023 at "Acta Oncologica"
DOI: 10.1080/0284186x.2023.2197121
Abstract: Abstract Objectives To facilitate high-quality register-based research on colorectal cancer (CRC) in Sweden by constructing a database consisting of CRC patients, matched comparators, and relatives. Material and methods Patients with adenocarcinoma in the colon and/or… read more here.
Keywords: colorectal adenocarcinoma; register; research; crc ... See more keywords