p62/sequestosome 1 in human colorectal carcinoma as a potent prognostic predictor associated with cell proliferation
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Medicine"
DOI: 10.1002/cam4.1093
Abstract: p62/sequestosome 1 (p62) is a multi‐domain protein that functions as a receptor for ubiquitinated targets in the selective autophagy and serves as a scaffold in various signaling cascades. p62 have been reported to be up‐regulated… read more here.
Keywords: cell proliferation; p62; colorectal carcinoma;
Implications of estrogen and its receptors in colorectal carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5242
Abstract: Estrogens have been implicated in the pathogenesis of various cancer types, including colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular signaling cascades followed by binding to estrogen, resulting in important changes… read more here.
Keywords: implications estrogen; estrogen; estrogen receptors; colorectal carcinoma ... See more keywords
Predictive Potential of PD-L1, TYMS, and DCC Expressions in Treatment Outcome of Colorectal Carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2020_521
Abstract: Colorectal carcinoma (CRC) is a malignancy of epithelial origin in the large bowel. The elucidation of the biological functions of programmed cell death ligand-1 (PD-L1), thymidylate synthase (TYMS), and deleted in colorectal cancer (DCC) biomarkers… read more here.
Keywords: tyms; colorectal carcinoma; tyms dcc; expression ... See more keywords
Ex vivo MR imaging of colorectal carcinoma before and after formalin fixation: correlation with histopathologic findings
Sign Up to like & getrecommendations! Published in 2018 at "Abdominal Radiology"
DOI: 10.1007/s00261-018-1538-8
Abstract: PurposeWe aimed to assess and compare ex vivo MRI of resected colorectal carcinoma before and after formalin fixation.MethodsWe enrolled 45 consecutive patients (47 carcinomas) who underwent colorectal carcinoma surgery. Specimens underwent two MR scans at… read more here.
Keywords: formalin fixation; fixation; colorectal carcinoma; carcinoma formalin ... See more keywords
Effects of increased accumulation of doxorubicin due to emodin on efflux transporter and LRP1 expression in lung adenocarcinoma and colorectal carcinoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-018-3346-4
Abstract: Treatment with doxorubicin (dox) and emodin, separately and together, under normoxic and hypoxia-like conditions induced by CoCl2, led to greater intracellular compound accumulation over 10 h post-addition in the presence of CoCl2 in lung adenocarcinoma (A549)… read more here.
Keywords: lung adenocarcinoma; accumulation; colorectal carcinoma; dox emodin ... See more keywords
Manilkara zapota (L.) P. Royen Leaf Extract Derived Silver Nanoparticles Induce Apoptosis in Human Colorectal Carcinoma Cells Without Affecting Human Lymphocytes or Erythrocytes
Sign Up to like & getrecommendations! Published in 2019 at "Biological Trace Element Research"
DOI: 10.1007/s12011-019-1653-6
Abstract: Plant-derived synthesis of silver nanoparticles (AgNPs) has found wide biomedical applications including cancer cure. This report deals with biosynthesis of silver nanoparticles (MZLAgNPs) employing leaf extracts of Manilkara zapota (L.) under optimized conditions. Characterization of… read more here.
Keywords: silver nanoparticles; carcinoma; apoptosis; microscopy ... See more keywords
Inhibition of microtubule assembly and cytotoxic effect of graphene oxide on human colorectal carcinoma cell HCT116.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.108940
Abstract: Nanomaterials, such as graphene oxide (GO), are increasingly being investigated for their suitability in biomedical applications. Tubulin is the key molecule for the formation of microtubules crucial for cellular function and proliferation, and as such… read more here.
Keywords: graphene oxide; microtubule; colorectal carcinoma; effect ... See more keywords
Chronic inflammatory demyelinating polyneuropathy as a paraneoplastic manifestation of colorectal carcinoma: What do we know?
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2021.102545
Abstract: The pathogenesis of chronic inflammatory demyelinating polyneuropathy (CIDP) remains highly debated among experts. In recent times, literature has divulged a riveting yet plausible association between colorectal carcinoma and CIDP as its paraneoplastic ramification. Initially, research… read more here.
Keywords: inflammatory demyelinating; demyelination; demyelinating polyneuropathy; colorectal carcinoma ... See more keywords
The role of appendectomy and cholecystectomy in the pathogenesis of colorectal carcinomas
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2021.102991
Abstract: Background Several alterations in the gastrointestinal tract which occur after appendectomy or cholecystectomy have been suggested to raise the risk of developing colorectal carcinoma. Given the frequency that these procedures are performed, we sought to… read more here.
Keywords: colorectal carcinomas; risk; colorectal carcinoma; appendectomy cholecystectomy ... See more keywords
Tumor budding in colorectal carcinoma: An institutional interobserver reliability and prognostic study of colorectal adenocarcinoma cases.
Sign Up to like & getrecommendations! Published in 2019 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2019.151420
Abstract: BACKGROUND Colorectal carcinomas are one of the most commonly diagnosed malignancies. There are many prognostic factors relating to clinical course and disease progression, including tumor stage, metastasis, and tumor budding. In 2016, the International Tumor… read more here.
Keywords: agreement; system; colorectal carcinoma; tumor budding ... See more keywords
Insights regarding novel biomarkers and the pathogenesis of primary colorectal carcinoma based on bioinformatic analysis
Sign Up to like & getrecommendations! Published in 2020 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2020.107229
Abstract: BACKGROUND Biomarkers are important in the study of tumor processes for early detection and precise treatment. The biomarkers that have been previously detected are not useful for clinical application for primary colorectal carcinoma (PCRC). The… read more here.
Keywords: analysis; colorectal carcinoma; primary colorectal; gene ... See more keywords