Alpha-lipoic Acid suppresses P2X receptor activities and visceral hypersensitivity to colorectal distention in diabetic rats
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DOI: 10.1038/s41598-017-04283-7
Abstract: The present study was designed to investigate the roles of P2X3 receptors in dorsal root ganglion (DRG) neurons in colonic hypersensitivity and the effects of alpha-lipoic acid (ALA) on P2X3 receptor activity and colonic hypersensitivity… read more here.
Keywords: hypersensitivity; alpha lipoic; diabetic rats; colorectal distention ... See more keywords
Relationship between sympathoadrenal and pituitary-adrenal response during colorectal distention in the presence of corticotropin-releasing hormone in patients with irritable bowel syndrome and healthy controls
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DOI: 10.1371/journal.pone.0199698
Abstract: Corticotropin-releasing hormone (CRH) mediates stress responses in the brain-gut axis. Administration of CRH modulates brain activation, for example by controlling the autonomic nervous system in response to colorectal distention. Here, we investigated the relationship between… read more here.
Keywords: hormone; response; distention; relationship ... See more keywords