Postoperative complications affect long‐term outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal carcinomatosis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.24632
Abstract: Morbidity after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS + HIPEC) for colorectal peritoneal carcinomatosis (PC) may negatively affect survival. The objective was to determine the impact of postoperative complications (CX) on survival in patients undergoing CRS + HIPEC… read more here.
Keywords: hyperthermic intraperitoneal; surgery hyperthermic; colorectal peritoneal; intraperitoneal chemotherapy ... See more keywords
Oncological impact of intraperitoneal chemotherapy after cytoreductive surgery for patients with colorectal peritoneal metastasis: A bi‐institutional retrospective analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.27171
Abstract: There is a paucity of evidence on the value of intraperitoneal chemotherapy (IPC) following cytoreductive surgery (CRS) for colorectal peritoneal metastasis. This study aimed to evaluate the association between mitomycin C‐IPC and survival outcomes following… read more here.
Keywords: colorectal peritoneal; cytoreductive surgery; intraperitoneal chemotherapy; peritoneal metastasis ... See more keywords
Oxaliplatin versus Mitomycin C following complete cytoreduction for colorectal peritoneal metastases: a comparative study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-019-04447-y
Abstract: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) can offer selected patients with colorectal peritoneal metastases (CRPM) a favorable long-term survival. While cytoreductive techniques are standardized, there remains great variability in HIPEC drugs with mitomycin… read more here.
Keywords: complete cytoreduction; colorectal peritoneal; peritoneal metastases; mitomycin ... See more keywords
Intraperitoneal collagenase as a novel therapeutic approach in an experimental model of colorectal peritoneal carcinomatosis
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DOI: 10.1038/s41598-020-79721-0
Abstract: The usefulness of local collagenase in therapeutic approaches to solid tumors has been tested recently. In this study, we evaluate the safety and efficacy of intraperitoneal collagenase associated or not to mitomycin for treatment of… read more here.
Keywords: collagenase; colorectal peritoneal; intraperitoneal collagenase; peritoneal metastases ... See more keywords
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases in an elderly population: outcomes from a single centre
Sign Up to like & getrecommendations! Published in 2022 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.17761
Abstract: The prevalence of elderly patients with resectable colorectal peritoneal metastases (CRPM) is increasing. This study aimed to compare short and long‐term outcomes of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for CRPM in patients… read more here.
Keywords: peritoneal metastases; colorectal peritoneal; surgery; intraperitoneal chemotherapy ... See more keywords
Randomized controlled trials in surgical resection of colorectal peritoneal metastases: Disentangling negativity in PRODIGE 7 and PROPHYLOCHIP
Sign Up to like & getrecommendations! Published in 2021 at "Colorectal Disease"
DOI: 10.1111/codi.15596
Abstract: Surgeons have been castigated for lack of enthusiasm and delivery of trials in surgical oncology (1). Trials are few and mis-interpretation common. Jonathon Swift, best known for "Gulliver's Travels", warned us years ago about misinterpretation… read more here.
Keywords: surgical resection; randomized controlled; colorectal peritoneal; trials surgical ... See more keywords
Results of a randomized phase 3 study evaluating the potential benefit of a second-look surgery plus HIPEC in patients at high risk of developing colorectal peritoneal metastases (PROPHYLOCHIP- NTC01226394).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.3531
Abstract: 3531Background: Complete cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) allow to prolong survival in patients with colorectal peritoneal metastases (CRPM)... read more here.
Keywords: surgery; colorectal peritoneal; results randomized; peritoneal metastases ... See more keywords
ASO Author Reflections: Toward Improved Selection of Patients for Cytoreduction and HIPEC: Identification of Prognostic Factors for Patients with Colorectal Peritoneal Metastases
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-018-6842-6
Abstract: Cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) improve survival of patients with colorectal peritoneal metastases (PM). Careful patient selection is pivotal because this treatment is associated with substantial morbidity, but current selection criteria fail to discriminate… read more here.
Keywords: colorectal peritoneal; selection; peritoneal metastases; cytoreduction hipec ... See more keywords
Diagnostic Laparoscopy as a Selection Tool for Patients with Colorectal Peritoneal Metastases to Prevent a Non-therapeutic Laparotomy During Cytoreductive Surgery
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-019-07957-w
Abstract: Objective The aim of this study was to evaluate the introduction of diagnostic laparoscopy (DLS) in patients with colorectal peritoneal metastases (PM) to prevent non-therapeutic laparotomies during cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS + HIPEC). Methods… read more here.
Keywords: colorectal peritoneal; dls; non therapeutic; cohort ... See more keywords
ASO Visual Abstract: Feasibility and Safety of Oxaliplatin-Based Pressurized Intraperitoneal Aerosol Chemotherapy with or Without Intraoperative Intravenous 5-Fluorouracil and Leucovorin for Colorectal Peritoneal Metastases: A Multicenter Comparative Cohort Study
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-022-11675-1
Abstract: This study (https://doi.org/10.1245/s10434-022-11577-2) included consecutive patients with histologically proven unresectable and isolated colorectal peritoneal metastases (cPM), treated with PIPAC-Ox in seven tertiary referral centers between January 2015 and April 2020. Toxicity events and oncological outcomes… read more here.
Keywords: intraoperative intravenous; feasibility; peritoneal metastases; study ... See more keywords
Detection of Experimental Colorectal Peritoneal Metastases by a Novel PDGFRβ-Targeting Nanobody
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DOI: 10.3390/cancers14184348
Abstract: Simple Summary Colorectal cancer can metastasize to multiple distant sites. Metastases growing within the peritoneal cavity cause a high degree of morbidity and are associated with very poor survival. Moreover, peritoneal metastases are difficult to… read more here.
Keywords: peritoneal metastases; colorectal peritoneal; detection; pdgfrb ... See more keywords