Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2120633119
Abstract: Significance This study uncovered the role of ZNF280C, a known DNA damage response protein, as a tumorigenic transcription regulator that contributes to colorectal tumorigenesis and metastasis through maintaining an epigenetic repression program at key cancer… read more here.
Keywords: maintaining epigenetic; colorectal tumorigenesis; epigenetic repression; contributes colorectal ... See more keywords
Microbial metabolites in colorectal tumorigenesis and cancer therapy
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DOI: 10.1080/19490976.2023.2203968
Abstract: ABSTRACT Trillions of microbes are indigenous to the human gastrointestinal tract, together forming an ecological community known as the gut microbiota. The gut microbiota is involved in dietary digestion to produce various metabolites. In healthy… read more here.
Keywords: tumorigenesis cancer; colorectal tumorigenesis; microbial metabolites; metabolites colorectal ... See more keywords
Interleukin‐13 and its signaling pathway is associated with obesity‐related colorectal tumorigenesis
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DOI: 10.1111/cas.14066
Abstract: The incidence of colorectal cancer (CRC) has been on the rise, which is linked to the increasing prevalence of obesity, based on global epidemiological evidence. Although chronic inflammation is implicated in tumor development, the mechanisms… read more here.
Keywords: related colorectal; colorectal tumorigenesis; obesity related; crc ... See more keywords