Immune escape of colorectal tumors via local LRH-1/Cyp11b1-mediated synthesis of immunosuppressive glucocorticoids.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13414
Abstract: Control of tumor development and growth by the immune system critically defines patient fate and survival. What regulates the escape of colorectal tumors from destruction by the immune system is currently unclear. Here, we investigated… read more here.
Keywords: cyp11b1 mediated; colorectal tumors; synthesis; glucocorticoid synthesis ... See more keywords
Bipolar-current needle-knife with a water jet function (Jet B-knife) shortens the procedure time of endoscopic submucosal dissection for colorectal tumors
Sign Up to like & getrecommendations! Published in 2020 at "Surgical Endoscopy"
DOI: 10.1007/s00464-020-07832-w
Abstract: Endoscopic submucosal dissection (ESD) is a technically difficult and time-consuming procedure for the treatment of large colorectal tumors. In Japan, the ball-tip bipolar-current needle-knife (BB-knife) has been used in ESD as a safe device that… read more here.
Keywords: knife; jet; jet knife; time ... See more keywords
Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors
Sign Up to like & getrecommendations! Published in 2017 at "Nature Genetics"
DOI: 10.1038/ng.3818
Abstract: Intratumoral heterogeneity is a major obstacle to cancer treatment and a significant confounding factor in bulk-tumor profiling. We performed an unbiased analysis of transcriptional heterogeneity in colorectal tumors and their microenvironments using single-cell RNA–seq from… read more here.
Keywords: single cell; heterogeneity; analysis; cell transcriptomes ... See more keywords
Epidermal growth factor receptor‐targeted molecular imaging of colorectal tumors: Detection and treatment evaluation of tumors in animal models
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DOI: 10.1111/cas.14020
Abstract: To overcome the problem of overlooking colorectal tumors, a new and highly sensitive modality of colonoscopy is needed. Moreover, it is also important to establish a new modality to evaluate viable tumor volume in primary… read more here.
Keywords: imaging colorectal; growth factor; epidermal growth; molecular imaging ... See more keywords
Challenges associated with the pathological diagnosis of colorectal tumors less than 10 mm in size
Sign Up to like & getrecommendations! Published in 2018 at "Digestive Endoscopy"
DOI: 10.1111/den.13038
Abstract: Various techniques including cold snare polypectomy and endoscopic mucosal resection are used for the removal of small colorectal polyps. Specimens of resected polyps are prepared in pathology laboratories and analyzed to make a pathological diagnosis.… read more here.
Keywords: pathological diagnosis; diagnosis; challenges associated; associated pathological ... See more keywords
Magnetic Resonance Imaging Characteristic Evaluation of Dexmedetomidine on Neurocognitive Dysfunction in Elderly Patients with Colorectal Tumors after Laparoscopic Operation
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/1345695
Abstract: In order to investigate the effects of Dexmedetomidine (DEX) on postoperative anesthesia recovery time and consciousness function in elderly patients with laparoscopic colorectal tumors, 40 patients (20 in the control group and 20 in the… read more here.
Keywords: colorectal tumors; operation; elderly patients; dex group ... See more keywords
Prophylactic Suturing Closure Is Recommended after Endoscopic Treatment of Colorectal Tumors in Patients with Antiplatelet/Anticoagulant Therapy
Sign Up to like & getrecommendations! Published in 2017 at "Oncology"
DOI: 10.1159/000481226
Abstract: The prophylactic closure of mucosal defects after endoscopic resection is known to prevent postoperative bleeding in colorectal lesions. However, closure of large mucosal defects is difficult with conventional clips only, and several closure techniques have… read more here.
Keywords: closure; prophylactic suturing; prophylactic closure; mucosal defects ... See more keywords
Erratum: Molecular profiling of colorectal tumors stratified by the histological tumor-stroma ratio - Increased expression of galectin-1 in tumors with high stromal content
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.26820
Abstract: [This corrects the article DOI: 10.18632/oncotarget.25845.]. read more here.
Keywords: profiling colorectal; molecular profiling; stratified histological; tumors stratified ... See more keywords
The quantitative profiling of blood mSEPT9 determines the detection performance on colorectal tumors.
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DOI: 10.2217/epi-2017-0154
Abstract: AIM To investigate the quantitative relationship between the positive detection rate (PDR) in colorectal tumor detection and the mSEPT9 level. MATERIALS & METHODS The level of blood mSEPT9 in various colorectal diseases was quantified by… read more here.
Keywords: msept9 level; msept9; detection; blood msept9 ... See more keywords
Colitis and colorectal tumors should be further explored and differentiated
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastrointestinal Oncology"
DOI: 10.4251/wjgo.v14.i8.1597
Abstract: The original article by Yuichi et al explored whether the Japan Narrow-Band Imaging Expert Team classification and the pit pattern classification are suitable for diagnosing neoplastic lesions in patients with ulcerative colitis. In this letter,… read more here.
Keywords: oncology; colitis colorectal; explored differentiated; colorectal tumors ... See more keywords