Abstract CT031: COM701 demonstrates preliminary antitumor activity as monotherapy and in combination with nivolumab in patients with advanced solid tumors
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DOI: 10.1158/1538-7445.am2020-ct031
Abstract: Introduction: COM701 is a novel first-in-class Immune checkpoint inhibitor (ICI) that binds with high affinity to poliovirus receptor related immunoglobulin domain containing (PVRIG) blocking its interaction with its ligand, PVRL2 and regulating the activity of… read more here.
Keywords: solid tumors; combination nivolumab; com701; arm ... See more keywords
A phase I study evaluating COM701 in patients with advanced solid tumors.
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DOI: 10.1200/jco.2019.37.15_suppl.tps2657
Abstract: TPS2657 Background: There is a high unmet medical need for the treatment (tx) of patients (pt) who are refractory to or relapse following tx with checkpoint inhibitors. Newer checkpoint therapies with novel mechanisms of action… read more here.
Keywords: antitumor activity; advanced solid; study; com701 ... See more keywords