Comparative analysis of the dual EGFR-DNA targeting and growth inhibitory properties of 6-mono-alkylamino- and 6,6-dialkylaminoquinazoline-based type II combi-molecules.
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DOI: 10.1016/j.ejmech.2020.112185
Abstract: Over the past decade, we described a novel tumour targeted approach that sought to design "combi-molecules" to hit two distinct targets in tumour cells. Here, to generate small combi-molecules with strong DNA damaging potential while… read more here.
Keywords: egfr; dna; combi; growth inhibitory ... See more keywords