Cytokines as potential combination agents with PD‐1/PD‐L1 blockade for cancer treatment
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29491
Abstract: Immunotherapy has caused a paradigm shift in the treatment of several malignancies, particularly the blockade of programmed death‐1 (PD‐1) and its specific receptor/ligand PD‐L1 that have revolutionized the treatment of a variety of malignancies, but… read more here.
Keywords: combination agents; cytokines potential; treatment; cancer ... See more keywords
P-1072. Evaluation of the Spontaneous Mutation Frequencies of SPR719 Alone and in Combination with Other Agents Used to Treat Mycobacterium avium Complex Pulmonary Disease
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DOI: 10.1093/ofid/ofae631.1260
Abstract: Abstract Background SPR720 (fobrepodacin), a novel oral benzimidazole prodrug that inhibits the ATPase activity of mycobacterial DNA gyrase B, is being developed for treatment of nontuberculous mycobacterial pulmonary disease (NTM-PD). SPR719, the active moiety of… read more here.
Keywords: fold mic; combination; combination agents; alone combination ... See more keywords
Carbapenem-Nonsusceptible Pseudomonas aeruginosa Isolates from Intensive Care Units in the United States: a Potential Role for New β-Lactam Combination Agents
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.00535-19
Abstract: Pseudomonas aeruginosa, a frequent pathogen in the intensive care unit (ICU), has the propensity to develop antibiotic resistance. In particular, carbapenem-nonsusceptible (NS) P. aeruginosa poses tremendous challenges, and new antibiotics will be needed to treat… read more here.
Keywords: aeruginosa isolates; lactam combination; aeruginosa; combination agents ... See more keywords