Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2017_73
Abstract: Nonhuman primate (NHP) models of AIDS represent a potentially powerful component of the effort to understand in vivo sources of AIDS virus that persist in the setting of suppressive combination antiretroviral therapy (cART) and to… read more here.
Keywords: antiretroviral therapy; combination antiretroviral; suppressive combination; nonhuman primate ... See more keywords
Do Combination Antiretroviral Therapy Regimens for HIV Infection Feature Diverse T-Cell Phenotypes and Inflammatory Profiles?
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DOI: 10.1093/ofid/ofaa340
Abstract: Abstract Immune abnormalities featuring HIV infection persist despite the use of effective combination antiretroviral therapy (cART) and may be linked to the development of noninfectious comorbidities. The aim of the present narrative, nonsystematic literature review… read more here.
Keywords: antiretroviral therapy; cart; hiv infection; combination antiretroviral ... See more keywords
Intolerance of dolutegravir-containing combination antiretroviral therapy: not just a pharmacokinetic drug interaction.
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DOI: 10.1097/qad.0000000000001394
Abstract: de Boer and colleagues [1] have recently reported the results of a postmarketing, ‘real-life,’ observational study, documenting a rate of discontinuation of dolutegravir (mainly for neuropsychological events) much higher than those reported previously in randomized… read more here.
Keywords: dolutegravir; containing combination; intolerance dolutegravir; dolutegravir containing ... See more keywords
Life expectancy of HIV‐positive people after starting combination antiretroviral therapy: a meta‐analysis
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DOI: 10.1111/hiv.12421
Abstract: Life expectancy is an important indicator informing decision making in policies relating to HIV‐infected people. Studies estimating life expectancy after starting combination antiretroviral therapy (cART) have noted differences between income regions. The objective of our… read more here.
Keywords: antiretroviral therapy; combination antiretroviral; starting combination; life ... See more keywords
Longitudinal Effects of Combination Antiretroviral Therapy on Cognition and Neuroimaging Biomarkers in Treatment-Naive People With HIV
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DOI: 10.1212/wnl.0000000000200829
Abstract: Background and Objectives While combination antiretroviral therapy (cART) has dramatically increased the life expectancy of people with HIV (PWH), nearly 50% develop HIV-associated neurocognitive disorders. This may be due to previously uncontrolled HIV viral replication,… read more here.
Keywords: cognition; antiretroviral therapy; people hiv; combination antiretroviral ... See more keywords
Erythrocyte Inosine triphosphatase activity: A potential biomarker for adverse events during combination antiretroviral therapy for HIV
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DOI: 10.1371/journal.pone.0191069
Abstract: The purine analogues tenofovir and abacavir are precursors of potential substrates for the enzyme Inosine 5’-triphosphate pyrophosphohydrolase (ITPase). Here, we investigated the association of ITPase activity and ITPA genotype with the occurrence of adverse events… read more here.
Keywords: antiretroviral therapy; itpase activity; combination antiretroviral; adverse events ... See more keywords
Persistence of Activated and Adaptive-Like NK Cells in HIV+ Individuals despite 2 Years of Suppressive Combination Antiretroviral Therapy
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DOI: 10.3389/fimmu.2017.00731
Abstract: Innate immune dysfunction persists in HIV+ individuals despite effective combination antiretroviral therapy (cART). We recently demonstrated that an adaptive-like CD56dim NK cell population lacking the signal transducing protein FcRγ is expanded in HIV+ individuals. Here,… read more here.
Keywords: antiretroviral therapy; combination antiretroviral; individuals despite; hiv individuals ... See more keywords
Combination Antiretroviral Therapy (cART) in Diabetes Exacerbates Diabetogenic Effects on Hippocampal Microstructure, Neurogenesis and Cytokine Perturbation in Male Sprague Dawley Rats
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DOI: 10.3390/diagnostics12040905
Abstract: The increasing incidence of diabetes and HIV/AIDS–diabetes comorbidity in society has led to the prevalence of combination antiretroviral therapy (cART) in diabetes, with some reported neural effects. Therefore, the effects of cART and type two… read more here.
Keywords: cart diabetes; therapy cart; antiretroviral therapy; male sprague ... See more keywords
Combination Antiretroviral Therapy and Immunophenotype of Feline Immunodeficiency Virus
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DOI: 10.3390/v15040822
Abstract: Feline Immunodeficiency Virus (FIV) causes progressive immune dysfunction in cats similar to human immunodeficiency virus (HIV) in humans. Although combination antiretroviral therapy (cART) is effective against HIV, there is no definitive therapy to improve clinical… read more here.
Keywords: immunodeficiency virus; combination antiretroviral; therapy; immunodeficiency ... See more keywords