Highly expressed EZH2 in combination with BAP1 and MTAP loss, as detected by immunohistochemistry, is useful for differentiating malignant pleural mesothelioma from reactive mesothelial hyperplasia.
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DOI: 10.1016/j.lungcan.2019.02.004
Abstract: OBJECTIVE Malignant pleural mesothelioma (MPM) is an aggressive neoplasm with poor prognosis. Loss of BRCA-associated protein 1 (BAP1) protein expression as detected by immunohistochemistry (IHC) and homozygous deletion (HD) of the 9p21 locus as detected… read more here.
Keywords: mpm; bap1 mtap; combination bap1; bap1 ... See more keywords